Meperidine: Difference between revisions
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==Indications by Condition== | |||
''The following table is automatically generated from disease/condition pages across WikEM.'' | |||
{{#ask:[[Has DrugName::Meperidine]] | |||
|?Has Indication=Indication | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|?Has Route=Route | |||
|?Has Population=Population | |||
|format=broadtable | |||
|headers=plain | |||
|link=subject | |||
|sort=Has Indication | |||
|limit=50 | |||
}} | |||
Revision as of 16:43, 20 March 2026
General
- Type: opioid
- Dosage Forms: PO, SC,IM,IV
- Common Trade Names: Demerol
Adult Dosing
General
Pain:
- 50-150mg PO/SC/IM/IV q3-4h: decrease dose if given IV. Seizure risk if dose > 600mg in 24 hours.
Pediatric Dosing
Pain: 1-1.75mg/kg PO/SC/IM q3-4h, max 100mg/dose
Special Populations
- Pregnancy Rating: B
- Lactation Risk Categories: safe
- Renal Dosing
- Adult: CrCl 10-50: decrease dose 25%, if CrCl < 10: decrease dose 50%
- Pediatric: CrCl 10-50: decrease dose 25%, if CrCl < 10: decrease dose 50%
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- MAOI use within 14 days
- Respiratory depression
Adverse Reactions
Serious
- Respiratory Depression
- Apnea
- Hypotension
- syncope
- bradycardia
- urinary retention
- Seizures
- anaphylaxis
Common
- Nausea
- Rash
- Headache
- Fatigue
- xerostomia
- constipation
- Tremor
- urinary retention
Pharmacology
- Half-life: 3-5 hour
- Metabolism: Liver
- Excretion: urine
- Mechanism of Action:binds to various opioid receptors
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population | |
|---|---|---|---|---|---|
| Acute pain management#Meperidine Step 3 - Severe pain (opioid, avoid if possible) Adult | Acute pain management | 1.0-1.5 mg/kg IV/IM; titrate 12.5-50 mg IV increments | Step 3 - Severe pain (opioid, avoid if possible) | IV/IM | Adult |