Theophylline: Difference between revisions
| Line 9: | Line 9: | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*Lactation: | *Lactation: Probably Safe | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult: no adjustment | ||
**Pediatric | **Pediatric: <3 mo: decr. dose amount not defined; >3 mo: no adjustment | ||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult: decr. dose amount not defined | ||
**Pediatric | **Pediatric: decr. dose amount not defined | ||
==Contraindications== | ==Contraindications== | ||
Revision as of 22:21, 30 June 2015
General
- Type:
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation: Probably Safe
- Renal Dosing
- Adult: no adjustment
- Pediatric: <3 mo: decr. dose amount not defined; >3 mo: no adjustment
- Hepatic Dosing
- Adult: decr. dose amount not defined
- Pediatric: decr. dose amount not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: 8h
- Metabolism: liver; CYP450: 1A2, 2E1, 3A3
- Excretion: urine (10% unchanged)
- Mechanism of Action: exact mechanism unknown; increases cAMP; antagonizes adenosine receptors (methylxanthine)