Theophylline: Difference between revisions
| Line 23: | Line 23: | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*seizures | |||
*arrhythmias | |||
*hypotension | |||
*shock | |||
*exfoliative dermatitis | |||
===Common=== | ===Common=== | ||
Revision as of 22:22, 30 June 2015
General
- Type:
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation: Probably Safe
- Renal Dosing
- Adult: no adjustment
- Pediatric: <3 mo: decr. dose amount not defined; >3 mo: no adjustment
- Hepatic Dosing
- Adult: decr. dose amount not defined
- Pediatric: decr. dose amount not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- seizures
- arrhythmias
- hypotension
- shock
- exfoliative dermatitis
Common
Pharmacology
- Half-life: 8h
- Metabolism: liver; CYP450: 1A2, 2E1, 3A3
- Excretion: urine (10% unchanged)
- Mechanism of Action: exact mechanism unknown; increases cAMP; antagonizes adenosine receptors (methylxanthine)