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| === Overview table ===
| | #REDIRECT[[Emergency medicine podcasts]] |
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| {| class="wikitable"
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| |-
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| ! Class
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| ! Known as
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| ! Examples
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| ! Mechanism
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| ! Clinical uses
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| |-
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| ! Ia
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| | fast-channel blockers-Affect QRS complex
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| *Quinidine
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| *Procainamide
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| *Disopyramide
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| | (Na<sup>+</sup>) channel block (intermediate association/dissociation)
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| *Ventricular arrhythmias
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| *prevention of paroxysmal Recurrent atrial fibrillation (triggered by Vagus nerve overactivity)
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| *procainamide in [[Wolf Parkinson White (WPW)]]
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| ! Ib- Do not affect QRS complex
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| *Lidocaine
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| *Phenytoin
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| *Mexiletine
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| *Tocainide
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| | (Na<sup>+</sup>) channel block (fast association/dissociation)
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| *treatment and prevention during and immediately after Myocardial infarction, though this practice is now discouraged given the increased risk of Asystole
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| *Ventricular tachycardia
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| *Atrial fibrillation
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| ! Ic
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| *Flecainide
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| *Propafenone
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| *Moricizine
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| | (Na<sup>+</sup>) channel block (slow association/dissociation)
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| *prevents Paroxysmal atrial fibrillation
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| *treats Recurrent tachyarrhythmias of abnormal conduction system.
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| *contraindicated immediately post-myocardial infarction.
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| ! II
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| | Beta-blockers
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| *Propranolol
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| *Esmolol
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| *Timolol
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| *Metoprolol
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| *Atenolol
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| *Bisoprolol
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| | beta blocking<br>Propranolol also shows some class I action
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| *decrease Myocardial infarction mortality
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| *prevent recurrence of Tachyarrhythmias
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| ! III
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| *Amiodarone
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| *Sotalol
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| *Ibutilide
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| *Dofetilide
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| *Dronedarone
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| *E-4031
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| K<sup>+</sup> channel blocker
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| Sotalol is also a beta blocker
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| Amiodarone has Class I, II, and III activity
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| *In [[Wolf Parkinson White (WPW)]]
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| *(sotalol:) Ventricular tachycardias and Atrial fibrillation
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| *(Ibutilide:) Atrial flutter and Atrial fibrillation
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| ! IV
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| | slow-channel blockers
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| *Verapamil
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| *Diltiazem
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| | Ca<sup>2+</sup> channel blocker
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| *prevent recurrence of Paroxysmal supraventricular tachycardia
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| *reduce Ventricular rate in patients with Atrial fibrillation
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| ! V
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| *Adenosine
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| *Digoxin
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| *Magnesium Sulfate
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| | Work by other or unknown mechanisms (Direct nodal inhibition).
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| | Used in supraventricular arrhythmias, especially in Heart Failure with Atrial Fibrillation, contraindicated in ventricular arrhythmias. Or in the case of Magnesium Sulfate, used in Torsade de Pointe.
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| |}
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