Physostigmine: Difference between revisions

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==Pediatric Dosing==
==Pediatric Dosing==


*.02mg/kg every, repeat every 5-10 minutes until adequate response, max of 2 mg
*.02mg/kg repeat every 5-10 minutes until adequate response, max of 2 mg
* no faster than .5 mg/min


==Special Populations==
==Special Populations==

Revision as of 21:03, 30 December 2015

General

  • Type: acetylcholinesterase inhibitor
  • Dosage Forms:
  • Common Trade Names:

Adult Dosing

Anticholinergic toxicity

  • 0.5-2mg IV over 5min

Pediatric Dosing

  • .02mg/kg repeat every 5-10 minutes until adequate response, max of 2 mg
  • no faster than .5 mg/min

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Side effects: bradycardia, dysrhythmias, cholinergic excess
    • Always have atropine at the bedside for bradycardia or cholinergic excess

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:
  • Onset of action: 15-20min

See Also

Sources