Intralipid: Difference between revisions
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==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
===Common=== | ===Common=== | ||
*Pancreatitis<ref name = review> Kostic MA and Gorelick M. Review of the use of lipid emulsion in nonlocal anesthetic poisoning. Pediatric Emergency Care 2014;30:427-436</ref> | |||
*Hypertriglyceridemia<ref name=review></ref> | |||
==Pharmacology== | ==Pharmacology== | ||
Revision as of 04:05, 9 January 2016
General
- Type: Lipid emulsion
- Dosage Forms: 20% fat emulsion
- Routes of Administration: IV
- Common Trade Names: Intralipid
- Emergency department indications: Local anesthetic systemic toxicity, refractory hemodynamic instability 2/2 ingestion of cardiodepressive medications / toxins (i.e. Beta blocker or Calcium Channel Blocker)
Adult Dosing
- 1.5 ml/kg bolus[1]
- Followed by 0.25 ml/kg/min for 20 min or until hemodynamic stability is achieved.[2]
Pediatric Dosing
Special Populations
- Pregnancy Rating: C
- Lactation risk:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Comments
See Also
External Links
References
- ↑ Cave, G. Intravenous Lipid Emulsion as Antidote Beyond Local Anesthetic Toxicity: A Systematic Review. 2009. 16(9)815–824
- ↑ Dillane D, Finucane BT. Local anesthetic systemic toxicity. Can J Anaesth. 2010 Apr;57(4):368-80.
- ↑ 3.0 3.1 Kostic MA and Gorelick M. Review of the use of lipid emulsion in nonlocal anesthetic poisoning. Pediatric Emergency Care 2014;30:427-436