Anion Gap and Osmolar Gap (High): Difference between revisions
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*[[Anion Gap (High)]] | *[[Anion Gap (High)]] | ||
*[[Toxidromes]] | *[[Toxidromes]] | ||
==External Links== | |||
*[http://www.mdcalc.com/serum-osmolality-osmolarity/ MDCalc - Serum Osmolality/Osmolarity] | |||
*[http://www.mdcalc.com/anion-gap/ MDCalc - Anion Gap] | |||
==References== | |||
<references/> | |||
[[Category:FEN]] | [[Category:FEN]] | ||
[[Category:Tox]] | [[Category:Tox]] | ||
Revision as of 18:21, 19 February 2016
Calculations
Anion Gap
AG = Na - (Cl + HCO3)
Calculated Osm
Calculated Osm = 2 x Na + (glu/18) + (BUN/2.8) + (ethanol/4.6) + (methanol/2.6) + (ethylene glycol/5) + (acetone/5.5) + (isopropanol/5.9)
- Normal = 275-295
Osmolal Gap
Osmolal Gap = measured osm - calculated osm
- Normal = (-)14-10 mOsm/L
Differential Diagnosis
Toxicological
- Methanol
- Ethanol glycol
- Aspirin (Salicylate) Toxicity
- Iron
- INH
- Paraldehyde
- Alcoholic Ketoacidosis
- Inhalants - CN, CO, Hydrogen Sulfide
- Toluene
Non-Toxicological
CAT MUDPILERS
- C-Cyanide
- A-ASA, Alcohol
- T-Toluene
- M-Methanol, Metformin
- U-Uremia
- D-DKA
- P-Paraldehyde, Post-ictal lactic acidosis (transient, 60-90 min), Phenformin (withdrawn in 1970s)
- I-Iron, INH, Inhalants, Inborn Errors
- L-Lactic Acidosis
- E-Ethylene glycol, Ethanol
- R-Rhabdomyolysis
- S-Salicylates, Solvents, Starvation