Flunitrazepam toxicity: Difference between revisions
| Line 22: | Line 22: | ||
==See Also== | ==See Also== | ||
*[[Benzodiazepines]] | *[[Benzodiazepines]] | ||
*[[Sedative/hypnotic toxicity]] | |||
==External Links== | ==External Links== | ||
Revision as of 08:28, 18 April 2016
Background
- Also known as Rohypnol
- Used in Europe and Asia for Insomnia and Pre-op sedation
- Used in US as "date-rape" agent
- An intermediate acting benzodiazepine
- Has strong affinity for benzodiazepine receptor
Clinical Features
- CNS depression within 30 minutes
- Patients can usually be aroused with noxious stimuli
- Half life 16-35 hours but coma can last 48h
Differential Diagnosis
Sedative/hypnotic toxicity
- Absinthe
- Barbiturates
- Benzodiazepines
- Chloral hydrate
- Gamma hydroxybutyrate (GHB)
- Baclofen toxicity
- Opioids
- Toxic alcohols
- Xylazine toxicity
Diagnosis
Management
Disposition
See Also
External Links
References
- Rosen's