D-dimer: Difference between revisions
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==See Also== | ==See Also== | ||
*[[Pulmonary Embolism (PE)]] | *[[Pulmonary Embolism (PE)]] | ||
==External Links== | |||
*[http://www.ncbi.nlm.nih.gov/pubmed/22284935 D-dimer threshold increase. Kline et. al.] | |||
==References== | ==References== | ||
<references/> | |||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Pulmonary]] | [[Category:Pulmonary]] | ||
[[Category:Vascular]] | [[Category:Vascular]] | ||
Revision as of 19:37, 26 April 2016
Differential Diagnosis
- Factors that can cause false-negative D-dimer
- Symptoms of PE > 3 days
- Small PE
- Use of qualitative latex fixation test
- Use of anticoagulants
- Factors that can cause false-positive D-dimer
- Cancer and malignancy
- Recent surgery
- Infection (eg, PNA, sepsis)
- Pregnancy
- Age > 70 years
- DIC
- Trauma
- Arterial thrombosis
- ACS/AMI
- Vaso-occlusive sickle cell crisis
- Acute CVA
- Vasculitis
- Superficial phlebitis
Diagnosis
- Traditional cutoff value = 500
- Age-adjusted (for over 50 years old) = age x 10
- Maintains high sensitivity while increasing specificity[1]
See Also
External Links
References
- ↑ Sharp AL, et al. An Age-Adjusted D-dimer Threshold for Emergency Department Patients with Suspected Pulmonary Embolus: Accuracy and Clinical Implications. Feb 2016. Annals of EM. 67(2);249-257.