Aplastic anemia: Difference between revisions
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==Background== | ==Background== | ||
*decrease hematopoietic precursor cells pancytopenia | *absence or decrease number of hematopoietic precursor cells --> pancytopenia ([[anemia]], [[thrombocytopenia]], neutropenia) | ||
*causes | *causes | ||
**drug-induced (chloramphenicol, carbamazepine, | **drug-induced ([[chloramphenicol]], [[carbamazepine]], [[valproic acid]], [[phenytoin]]) | ||
**viral infection ([[parvovirus B19]], [[HIV]], hepatitis), especially in patients w/ sickle cell disease or immunocompromise | **viral infection ([[parvovirus B19]], [[HIV]], hepatitis), especially in patients w/ sickle cell disease or immunocompromise | ||
**autoimmune | **autoimmune | ||
Revision as of 00:01, 11 July 2016
Background
- absence or decrease number of hematopoietic precursor cells --> pancytopenia (anemia, thrombocytopenia, neutropenia)
- causes
- drug-induced (chloramphenicol, carbamazepine, valproic acid, phenytoin)
- viral infection (parvovirus B19, HIV, hepatitis), especially in patients w/ sickle cell disease or immunocompromise
- autoimmune
- congenital (Fanconi anemia)