Meclizine: Difference between revisions
Neil.m.young (talk | contribs) (Text replacement - "==Sources==" to "==References==") |
Neil.m.young (talk | contribs) (Text replacement - "2 mg" to "2mg") |
||
| Line 1: | Line 1: | ||
==General== | ==General== | ||
*Type: [[Antihistamine]], H1 antagonist | *Type: [[Antihistamine]], H1 antagonist | ||
*Dosage Forms: 12.5, 25, | *Dosage Forms: 12.5, 25, 32mg oral tablet; 25 mg oral chewable tablet | ||
*Common Trade Names: Univert, Vertin-32, Dramamine less drowsy, Motion-Time | *Common Trade Names: Univert, Vertin-32, Dramamine less drowsy, Motion-Time | ||
Revision as of 19:23, 19 July 2016
General
- Type: Antihistamine, H1 antagonist
- Dosage Forms: 12.5, 25, 32mg oral tablet; 25 mg oral chewable tablet
- Common Trade Names: Univert, Vertin-32, Dramamine less drowsy, Motion-Time
Adult Dosing
Vertigo
- 25mg PO QID
Motion Sickness
- 25-100 mg PO 1 hour before activity. May repeat q24h
Pediatric Dosing
- >= 12 yrs old: Adult dosing
- < 12 yrs: No dosing specified in drug insert
Special Populations
- Pregnancy Rating: B
- Lactation: Excretion in breast milk unknown
- Renal Dosing: n/a
- Hepatic Dosing: n/a
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- CNS depression
- Caution in asthma, glaucoma, BPH, pyloric obstruction
Common
- Drowsiness, fatigue
Pharmacology
- Onset: 1 hour
- Half-life: 5 hours
- Metabolism: Hepatic
- Excretion: Urine and feces
- Mechanism of Action: Central anticholinergic; blocks chemoreceptor trigger zone. Decreases middle ear excitability, blocks vestibular-cerebellar pathways
See Also
References
Lexicomp