Subglottic stenosis: Difference between revisions

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==Background==
==Background==
*Subglottic Stenosis is a narrowing of the trachea directly inferior to the vocal cords.
[[File:Cross section of a trachea and esophagus.png|thumb|Cross section of a trachea and esophagus anatomy.]]
*Causes:
[[File:Blausen 0865 TracheaAnatomy.png|thumb|Tracheal anatomy.]]
**Idiopathic (more likely to affect females)
*A narrowing of the trachea directly inferior to the vocal cords
**Congenital abnormality in newborns
 
**Past mechanical trauma to the airway (intubation or surgery)
===Causes===
**Autoimmune disorders  
*Idiopathic (more likely to affect females)
**Wegener granulomatosis/ GPA - Approximately 36% of patients with GPA develop subglottic stenosis <ref>Taylor SC, Clayburgh DR, Rosenbaum JT, Schindler JS. Progression and management of Wegener's granulomatosis in the head and neck. Laryngoscope 2012; 122:1695.</ref>
*Congenital abnormality in newborns
**Rheumatoid Arthritis
*Past mechanical trauma to the airway ([[intubation]] or surgery)
**Sarcoidosis
*Autoimmune disorders  
*[[Wegener's granulomatosis]]/ GPA - Approximately 36% of patients with GPA develop subglottic stenosis <ref>Taylor SC, Clayburgh DR, Rosenbaum JT, Schindler JS. Progression and management of Wegener's granulomatosis in the head and neck. Laryngoscope 2012; 122:1695.</ref>
*[[Rheumatoid arthritis]]
*[[Sarcoidosis]]


==Clinical Features==
==Clinical Features==
*Tachypnea/ Dyspnea/ Hypoxia
*Tachypnea/ [[dyspnea]]/ [[hypoxia]]
*Inspiratory stridor
*Inspiratory [[stridor]]
*Hoarseness/ Dysphonia
*Hoarseness/ [[dysphonia]]
*Respiratory accessory muscle usage
*Respiratory accessory muscle usage
*Cough
*[[Cough]]
*"Tightness" in the neck
*"Tightness" in the neck
*Patients with history of greater than 1 week of intubation
*Patients with history of greater than 1 week of intubation


==Differential Diagnosis==
==Differential Diagnosis==
*Vocal cord paralysis
{{Stridor DDx}}
*Subglottic hemangioma
*Tumor (metastatic, benign airway tumors, primary endoluminal malignancies)
*Vascular ring
*Smoke injury
*Chemical burn
*Foreign body
*Tracheal stenosis (not at the subglottic region)
*Tracheomalacia<ref> Ernst A, Feller-Kopman D, Becker HD, Mehta AC. Central airway obstruction. Am J Respir Crit Care Med 2004</ref>


==Evaluation==
==Evaluation==
*Direct visualization via scope [[File:Subglottic_stenosis2.jpg]]
*Direct visualization via scope
*CT Neck
*CT Neck


==Management==
==Management==
*ENT referral or immediate securing of airway dependent upon respiratory distress
*ENT referral or immediate securing of airway dependent upon respiratory distress
*Humidified oxygen
*Humidified [[oxygen]]
*Proton pump inhibitor
*[[Proton pump inhibitor]]
*Systemic steroids
*Systemic [[steroids]]
*Treat underlying disorder if caused by autoimmune disorder
*Treat underlying disorder if caused by autoimmune disorder


Definitive Management:
Definitive Management:
*Dilation
*Dilation
*Crichotracheal resection
*Cricotracheal resection
*Tracheotomy
*Tracheotomy


==Disposition==
==Disposition==
 
*Admit


==See Also==
==See Also==

Latest revision as of 19:42, 17 January 2024

Background

Cross section of a trachea and esophagus anatomy.
Tracheal anatomy.
  • A narrowing of the trachea directly inferior to the vocal cords

Causes

Clinical Features

  • Tachypnea/ dyspnea/ hypoxia
  • Inspiratory stridor
  • Hoarseness/ dysphonia
  • Respiratory accessory muscle usage
  • Cough
  • "Tightness" in the neck
  • Patients with history of greater than 1 week of intubation

Differential Diagnosis

Stridor

Trauma

Infectious Disorders

Abscesses

Neoplastic Disorders

  • Neoplasms/tumors

Allergic and Auto-Immune Disorders

  • Spasmodic/tracheobronchitis
  • Angioedema/Angioneurotic edema

Metabolic, Storage Disorders

  • Cerebral Gaucher's of infants (acute)
  • Tracheobronchial amyloidosis

Biochemical Disorders

Congenital, Developmental Disorders

Psychiatric Disorders

  • Somatization disorder

Anatomical or Mechanical

Vegetative, Autonomic, Endocrine Disorders

Poisoning

Chronic Pediatric Conditions

Evaluation

  • Direct visualization via scope
  • CT Neck

Management

  • ENT referral or immediate securing of airway dependent upon respiratory distress
  • Humidified oxygen
  • Proton pump inhibitor
  • Systemic steroids
  • Treat underlying disorder if caused by autoimmune disorder

Definitive Management:

  • Dilation
  • Cricotracheal resection
  • Tracheotomy

Disposition

  • Admit

See Also

External Links

References

  1. Taylor SC, Clayburgh DR, Rosenbaum JT, Schindler JS. Progression and management of Wegener's granulomatosis in the head and neck. Laryngoscope 2012; 122:1695.
  2. Vocal Cord Dysfunction on Internet Book of Critical Care https://emcrit.org/ibcc/vcd/
  3. Ernst A, Feller-Kopman D, Becker HD, Mehta AC. Central airway obstruction. Am J Respir Crit Care Med 2004