Antihistamines: Difference between revisions

Latest revision as of 22:33, 7 March 2021

Also known as histamine antagonists
In common use, the term antihistamine refers only to compounds that inhibit action at the H₁ receptor (and not H₂, etc.).

Sedation
- Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness

Authors:

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-#[[Diphenhydramine]] (Benadryl)
+==Background==
-#Brompheniramine (Dimetane)
+*Also known as histamine antagonists
-#Loratadine (Claritin, Alavert)
+*In common use, the term antihistamine refers only to compounds that inhibit action at the H<sub>1</sub> receptor (and not H<sub>2</sub>, etc.).
-#Certirizine (Zyrtec)
+==Types==
+===H<sub>1</sub> antagonists===
+*[[Brompheniramine]] (Dimetane)
+*[[Cetirizine]] (Zyrtec)
+*[[Dimenhydrinate]]
+*[[Diphenhydramine]] (Benadryl)
+*[[Doxylamine]]
+*[[Fexofenadine]] (Allegra)
+*[[Hydroxyzine]] (Vistaril)
+*[[Loratadine]] (Claritin)
+*[[Meclizine]]
+===H<sub>2</sub> antagonists===
+*[[Cimetidine]]
+*[[Famotidine]]
+*[[Nizatidine]]
+*[[Ranitidine]]
+*[[Roxatidine]]
+==Indications==
+*H<sub>1</sub> antagonists
+**[[Allergic reactions]]
+**[[Insomnia]]
+**[[Vertigo]]
+**[[Motion sickness]]
+**[[Nausea and vomiting in pregnancy]]
+*H<sub>2</sub> antagonists
+**[[GERD]]/[[peptic ulcers]]
+**[[Allergic reactions]]
+==Side Effects==
+*Sedation
+**Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness
+==See Also==
+*[[Anticholinergic toxicity]]
+==References==
+<references/>
+[[Category:Pharmacology]]