Template:Typhoid Antibiotics: Difference between revisions

Latest revision as of 13:06, 20 March 2026

Oral therapy with Quinolone Susceptibility

Ciprofloxacin 500-750 mg PO q 12 hrs x 14 days

Parenteral Therapy with Quinolone Susceptibility

Ciprofloxacin 400 mg IV q 12 hrs x 10 days

Parenteral Therapy with Quinolone Resistance

if nalidixic acid resistant, assume fluoroquinolone resistant

Ceftriaxone 2g IV q 24 hrs x 14 days

OR

Cefixime 10-15 mg/kg IV q 12 hrs x 8 days

Oral Therapy with Quinolone Resistance

Azithromycin 1 g PO daily x 5 days
Amoxicillin Not 1st line treatment; 50-100mg/kg/day PO divided q6-8h x 14 days; First Dose: 12.5mg-33.3mg/kg PO x 1
Amoxicillin Not 1st line treatment; 50-100mg/kg/day PO divided q6-8h x 14 days

Pediatric

Ceftriaxone 50-80mg/kg IV daily x 10-14 days (max 2g)
Azithromycin 10-20mg/kg PO daily x 5-7 days (max 1g)
Cefixime 15-20mg/kg/day PO divided BID x 7-14 days (max 400mg/dose)

@@ Line 1: / Line 1: @@
-'''Oral therapy with Quinolone Susceptibility:'''
+====Oral therapy with [[Quinolone]] Susceptibility====
-*Ciprofloxacin 500-750 mg PO q 12 hrs x 14 days
+*{{AntibioticDose|disease=Typhoid fever|drug=Ciprofloxacin|dose=500-750 mg PO q 12 hrs x 14 days|context=Quinolone Susceptible, Oral}}
+====Parenteral Therapy with [[Quinolone]] Susceptibility====
-'''Parenteral Therapy with Quinolone Susceptibility: '''
+*{{AntibioticDose|disease=Typhoid fever|drug=Ciprofloxacin|dose=400 mg IV q 12 hrs x 10 days|context=Quinolone Susceptible, Parenteral}}
-*Ciprofloxacin 400 mg IV q 12 hrs x 10 days
+====Parenteral Therapy with [[Quinolone]] Resistance====
+:''if nalidixic acid resistant, assume [[fluoroquinolone]] resistant''
-'''Parenteral Therapy with Quinolone Resistance:'''
+*{{AntibioticDose|disease=Typhoid fever|drug=Ceftriaxone|dose=2g IV q 24 hrs x 14 days|context=Quinolone Resistant, Parenteral}}
+::'''OR'''
+*{{AntibioticDose|disease=Typhoid fever|drug=Cefixime|dose=10-15 mg/kg IV q 12 hrs x 8 days|context=Quinolone Resistant, Parenteral}}
+====Oral Therapy with [[Quinolone]] Resistance====
+*{{AntibioticDose|disease=Typhoid fever|drug=Azithromycin|dose=1 g PO daily x 5 days|context=Quinolone Resistant, Oral}}
+*{{AntibioticDose|drug=Amoxicillin|dose=''Not 1st line treatment''; 50-100mg/kg/day PO divided q6-8h x 14 days; First Dose: 12.5mg-33.3mg/kg PO x 1|context=Typhoid Fever|disease=Typhoid fever|population=Adult}}
+*{{AntibioticDose|drug=Amoxicillin|dose=''Not 1st line treatment''; 50-100mg/kg/day PO divided q6-8h x 14 days|context=Typhoid Fever (>3mo)|disease=Typhoid fever|population=Pediatric}}
-:''if nalidixic acid resistant, assume fluoroquinolone resistant''
+====Pediatric====
-*Ceftriaxone 2mg IV q 24 hrs x 14 days
+*{{AntibioticDose|disease=Typhoid fever|drug=Ceftriaxone|dose=50-80mg/kg IV daily x 10-14 days (max 2g)|context=Pediatric, Quinolone Resistant|population=Pediatric}}
-::'''OR'''
+*{{AntibioticDose|disease=Typhoid fever|drug=Azithromycin|dose=10-20mg/kg PO daily x 5-7 days (max 1g)|context=Pediatric, Oral|population=Pediatric}}
-*Cefixime 10-15 mg/kg IV q 12 hrs x 8 days
+*{{AntibioticDose|disease=Typhoid fever|drug=Cefixime|dose=15-20mg/kg/day PO divided BID x 7-14 days (max 400mg/dose)|context=Pediatric Oral Step-down|population=Pediatric}}
-'''Oral Therapy with Quinolone Resistance:'''
-*Azithromycin 1 g PO daily x 5 days