Template:Appendicitis Antibiotics: Difference between revisions
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<languages/> | <noinclude><languages/></noinclude> | ||
<translate> | <translate> | ||
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''Coverage should extend to [[Special:MyLanguage/E. coli|E. coli]], [[Special:MyLanguage/Klebsiella|Klebsiella]], [[Special:MyLanguage/Proteus|Proteus]], and [[Special:MyLanguage/Bacteroides|Bacteroides]] (an anaerobe)'' | ''Coverage should extend to [[Special:MyLanguage/E. coli|E. coli]], [[Special:MyLanguage/Klebsiella|Klebsiella]], [[Special:MyLanguage/Proteus|Proteus]], and [[Special:MyLanguage/Bacteroides|Bacteroides]] (an anaerobe)'' | ||
====Adult Simple Appendicitis==== | ====Adult Simple Appendicitis==== <!--T:2--> | ||
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''Antibiotic prophylaxis should be coordinated with surgical consult'' | ''Antibiotic prophylaxis should be coordinated with surgical consult'' | ||
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'''Options:''' | '''Options:''' | ||
*[[Special:MyLanguage/Cefoxitin|Cefoxitin]] 2g IV q6 hours OR | *[[Special:MyLanguage/Cefoxitin|Cefoxitin]] 2g IV q6 hours OR | ||
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====Pediatric Simple Appendicitis==== | ====Pediatric Simple Appendicitis==== <!--T:5--> | ||
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'''Options:''' | '''Options:''' | ||
*[[Special:MyLanguage/Cefoxitin|Cefoxitin]] 40mg/kg IV q6 hours | *[[Special:MyLanguage/Cefoxitin|Cefoxitin]] 40mg/kg IV q6 hours | ||
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====Complicated Appendicitis==== | ====Complicated Appendicitis==== <!--T:7--> | ||
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''Defined as perforation, abscess, or phlegmon'' | ''Defined as perforation, abscess, or phlegmon'' | ||
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'''Options:''' | '''Options:''' | ||
*[[Special:MyLanguage/Metronidazole|Metronidazole]] 500 mg IV q8hrs + | *[[Special:MyLanguage/Metronidazole|Metronidazole]] 500 mg IV q8hrs + | ||
Latest revision as of 10:43, 23 January 2026
Coverage should extend to E. coli, Klebsiella, Proteus, and Bacteroides (an anaerobe)
Adult Simple Appendicitis
Antibiotic prophylaxis should be coordinated with surgical consult
Options:
- Cefoxitin 2g IV q6 hours OR
- Cefotetan 2g IV q12 hours OR
- Moxifloxacin 400mg IV once daily OR
- Ertapenem 1g IV once daily
Pediatric Simple Appendicitis
Options:
- Cefoxitin 40mg/kg IV q6 hours
- Cefotetan 40mg/kg IV q12 hours
- Gentamicin 2.5mg/kg IV q8hrs +
- Metronidazole 7.5mg/kg IV 16hrs OR
- Clindamycin 10mg/kg IV q8hrs
Complicated Appendicitis
Defined as perforation, abscess, or phlegmon
Options:
- Metronidazole 500 mg IV q8hrs +
- Cefepime 50 mg/kg IV q12hrs OR
- Ciprofloxacin 400 mg IV q12hrs OR
- Levofloxacin 750 mg IV q24hrs OR
- Aztreonam 30 mg/kg IV q8hrs
- Imipenem/Cilastatin 25 mg/kg IV q6hrs (max 500mg)
- Meropenem 20 mg/kg IV q8hrs (max 1g)
- Piperacillin/Tazobactam 100 mg/kg (max 4.5g) IV q8hrs
Cautious use should be applied to use of fluoroquinolones in complicated pediatric appendicitis due to the risk of tendon injury