Template:Streptococcal Pharyngitis Antibiotics: Difference between revisions

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*[[Amoxicillin]] 50 mg/kg once daily (maximum = 1000 mg) for 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>
*[[Amoxicillin]] 50 mg/kg once daily (maximum = 1000 mg) for 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>


'''[[Penicillin]] allergic (mild):<ref name=Shulman12>Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82</ref>'''
'''[[Penicillin]] allergic (mild):'''
*[[Cephalexin]] 20 mg per kg PO BID (maximum 500 mg per dose) x 10 days
*[[Cephalexin]] 20 mg per kg PO BID (maximum 500 mg per dose) x 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>
*[[Cefadroxil]] 30 mg per kg PO QD (maximum 1 g daily) x 10 days
*[[Cefadroxil]] 30 mg per kg PO QD (maximum 1 g daily) x 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>


'''[[Penicillin]] allergic (anaphylaxis):<ref name=Shulman12>Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82</ref>'''
'''[[Penicillin]] allergic (anaphylaxis):<ref name=Shulman12>Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82</ref>'''
*[[Clindamycin]] 7.5mg/kg PO QID x 10d (child) or 450mg PO TID x 10d OR
*[[Clindamycin]] 7 mg/kg/dose TID (maximum = 300 mg/dose) x 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>
*[[Azithromycin]] 12mg/kg QD (child) or 500mg on day 1; then 250mg on days 2-5
*[[Azithromycin]] 12 mg/kg PO once (maximum = 500 mg), then 6 mg/kg (max=250 mg) once daily for the next 4 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>
*[[Clarithromycin]] 7.5 mg/kg/dose PO BID (maximum = 250 mg/dose) x 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref>

Latest revision as of 18:22, 28 January 2026

Treatment can be delayed for up to 9 days and still prevent major sequelae

Penicillin Options:

Penicillin allergic (mild):

  • Cephalexin 20 mg per kg PO BID (maximum 500 mg per dose) x 10 days[5]
  • Cefadroxil 30 mg per kg PO QD (maximum 1 g daily) x 10 days[6]

Penicillin allergic (anaphylaxis):[1]

  • Clindamycin 7 mg/kg/dose TID (maximum = 300 mg/dose) x 10 days[7]
  • Azithromycin 12 mg/kg PO once (maximum = 500 mg), then 6 mg/kg (max=250 mg) once daily for the next 4 days[8]
  • Clarithromycin 7.5 mg/kg/dose PO BID (maximum = 250 mg/dose) x 10 days[9]
  1. ↑ 1.0 1.1 1.2 Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82
  2. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
  3. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
  4. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
  5. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
  6. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
  7. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
  8. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
  9. ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
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