Hirudins: Difference between revisions
Ostermayer (talk | contribs) (Text replacement - "Category:Drugs" to "Category:Pharmacology") |
ClaireLewis (talk | contribs) (→Drugs) |
||
| (One intermediate revision by one other user not shown) | |||
| Line 5: | Line 5: | ||
*Hirudin | *Hirudin | ||
*Lepirudin | *Lepirudin | ||
*Argatroban | *[[Argatroban]] | ||
==Indications== | ==Indications== | ||
| Line 24: | Line 24: | ||
==References== | ==References== | ||
<references/> | |||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Latest revision as of 20:22, 22 September 2019
Background
- Direct thrombin inhibitors
Drugs
- Hirudin
- Lepirudin
- Argatroban
Indications
- HIT
- Unstable angina/NSTEMI/PCI
Complications
- Bleeding
- Majority of bleeding events occur at invasive sites
- No antidote available
- Minor bleeding
- Stop infusion
- Major bleeding
- Give FFP or PCC
Pharmacology
- Half-life is ~2hr
