Antihistamines: Difference between revisions
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**[[Insomnia]] | **[[Insomnia]] | ||
**[[Vertigo]] | **[[Vertigo]] | ||
**[[Motion sickness]] | |||
*H<sub>2</sub> antagonists | *H<sub>2</sub> antagonists | ||
**[[GERD]]/[[peptic ulcers]] | **[[GERD]]/[[peptic ulcers]] | ||
Revision as of 22:31, 7 March 2021
Background
- Also known as histamine antagonists
- In common use, the term antihistamine refers only to compounds that inhibit action at the H1 receptor (and not H2, etc.).
Types
H1 antagonists
- Brompheniramine (Dimetane)
- Cetirizine (Zyrtec)
- Dimenhydrinate
- Diphenhydramine (Benadryl)
- Doxylamine
- Fexofenadine (Allegra)
- Hydroxyzine (Vistaril)
- Loratadine (Claritin)
- Meclozine
H2 antagonists
Indications
- H1 antagonists
- H2 antagonists
Side Effects
- Sedation
- Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness