Cardiogenic shock: Difference between revisions

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***Decreases O2 demand BUT may worsen preload
***Decreases O2 demand BUT may worsen preload
*Coronary perfusion
*Coronary perfusion
**1. Small Fluid challenge
#Small Fluid challenge
**2. Increase inotropy  
#Increase inotropy  
***Titrate to CO (e.g. warm extremities)
***Titrate to CO (e.g. warm extremities)
***Dobutamine or Milrinone - if  
***Dobutamine or Milrinone - if  
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***CaCl 1gm
***CaCl 1gm
****Give if pt is hypocalcemic
****Give if pt is hypocalcemic
**3. Achieve MAP >65
#Achieve MAP >65
***Pressors
==Pressors==
 
{| class="wikitable"
|-
! Pressor !! Initial Dose !! Max Dose !! Cardiac Effect !! BP Effect !! Header text !! Header text
|-
| Example || Example || Example || Example || Example || Example || Example
|-
| Example || Example || Example || Example || Example || Example || Example
|-
| Example || Example || Example || Example || Example || Example || Example
|-
| Example || Example || Example || Example || Example || Example || Example
|-
| Example || Example || Example || Example || Example || Example || Example
|-
| Example || Example || Example || Example || Example || Example || Example
|}





Revision as of 00:10, 8 November 2013

Background

  • Leading cause of death in pts w/ MI who reach the hospital alive

Work-Up

  • Labs
    • Troponin
    • Lactate
    • CBC
    • Chem
    • BNP
      • <100 may rule-out cardiogenic shock
  • ECG
  • CXR
  • TTE

Etiology

  • Myocardial infarction
    • Pump failure
    • Mechanical complications
    • Acute MR (papillary muscle rupture)
    • VSD
    • Free-wall rupture
  • RV infarction
  • Decreased forward flow
    • Sepsis
    • Rate-related
      • Bradycardia
      • Tachycardia
    • Myocarditis
    • Myocardial contusion
    • Cardiomyopathy
  • Mechanical obstruction to forward flow
    • AS
    • HOCM
    • Mitral stenosis
    • Pericardial
  • LV regurgitation
    • Chordal rupture
    • Aortic insufficiency

DDX

  • MI
  • PE
  • COPD exacerbation
  • Peri/myocarditis
  • Aortic dissection
  • Pericardial tamponade
  • Acute valvular insufficiency
  • Sepsis
  • Hemorrhage
  • Toxins/drugs of abuse

Treatment

  • General
    • Intubation
      • Decreases O2 demand BUT may worsen preload
  • Coronary perfusion
  1. Small Fluid challenge
  2. Increase inotropy
      • Titrate to CO (e.g. warm extremities)
      • Dobutamine or Milrinone - if
        • Use milrinone if pt is on BB
      • CaCl 1gm
        • Give if pt is hypocalcemic
  1. Achieve MAP >65

Pressors

Pressor Initial Dose Max Dose Cardiac Effect BP Effect Header text Header text
Example Example Example Example Example Example Example
Example Example Example Example Example Example Example
Example Example Example Example Example Example Example
Example Example Example Example Example Example Example
Example Example Example Example Example Example Example
Example Example Example Example Example Example Example



  • Transfusion
    • Consider if Hb < 10
  • Specific
    • Mitral Regurg
      • Need to increase forward flow
        • Dobutamine (contractility)
        • Nitroprusside (afterload reduction)
    • MI
      • PCI or thrombolysis
    • Tox
      • Reverse CCB, BB, or dig toxicity

See Also

Source

Tintinalli

EMCrit Podcast 10