Typhoid fever: Difference between revisions
No edit summary |
Cathylewwho (talk | contribs) (background updated) |
||
| Line 1: | Line 1: | ||
==Background== | ==Background== | ||
Diagnosed in 2% of febrile travelers | |||
Caused by ''Salmonella enterica serotype Typhi'' (formerly ''Salmonella typhi'') ''serotype paratyphi A, B, and C'' | |||
Endemic in Mexico, Indonesia, Peru, and the Indian subcontinent | |||
Prior vaccination does not exclude infection | |||
Incubation period 1-3 weeks | |||
Chronic carrier state defined as organism in urine or stool > 12 months | |||
Chronic carrier state risk factors: biliary tract abnormalities | |||
==Diagnosis== | ==Diagnosis== | ||
Revision as of 02:42, 11 August 2014
Background
Diagnosed in 2% of febrile travelers
Caused by Salmonella enterica serotype Typhi (formerly Salmonella typhi) serotype paratyphi A, B, and C
Endemic in Mexico, Indonesia, Peru, and the Indian subcontinent
Prior vaccination does not exclude infection
Incubation period 1-3 weeks
Chronic carrier state defined as organism in urine or stool > 12 months
Chronic carrier state risk factors: biliary tract abnormalities
Diagnosis
- fvr, ha
- abd pain, constipation, -diarrhea rare
- leukopenia, thrombocytopenia, dry cough, LN
- insidious onset unlike dengue or rickettsia
- dx by blood cx for salmonella enterica serotype typhi
- serology unreliable
Differential Diagnosis
Fever in traveler
- Normal causes of acute fever!
- Malaria
- Dengue
- Leptospirosis
- Typhoid fever
- Typhus
- Viral hemorrhagic fevers
- Chikungunya
- Yellow fever
- Rift valley fever
- Q fever
- Amebiasis
- Zika virus
Treatment
- tx empirically with flouroquinolone or 3rd gen cephal
- vaccine partially effecive and breakthrough infc possible