Caffeine: Difference between revisions
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==Mechanism of Action== | ==Mechanism of Action== | ||
*Methylxanthine structure that antagonizes [[adenosine]] receptors | *Methylxanthine structure that antagonizes [[adenosine]] receptors | ||
==Indications by Condition== | |||
''The following table is automatically generated from disease/condition pages across WikEM.'' | |||
{{#ask:[[Has DrugName::Caffeine]] | |||
|?Has Indication=Indication | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|?Has Route=Route | |||
|?Has Population=Population | |||
|format=broadtable | |||
|headers=plain | |||
|mainlabel=- | |||
|sort=Has Indication | |||
|limit=50 | |||
}} | |||
==See Also== | ==See Also== | ||
Revision as of 21:24, 20 March 2026
General
- Type: Stimulant, Respiratory Stimulant, Nonselective Phosphodiesterase Enzyme Inhibitor
- Dosage Forms: tablets, capsules, lozenges, oral solution, injectable solution
- Dosage Strengths: tablets: 200 mg; capsules: 200 mg; lozenges: 75 mg; oral solution: 20 mg/mL; injectable solution: 20 mg/mL
- Routes of Administration: PO, IV, IM
- Common Trade Names: NoDoz, Recharge, Vivarin, Diurex, Cafcit
Common Dosages by Type
| Type | Amount | Caffeine^ |
| Coffee, brewed | 1 cup | 100mg |
| Coffee, instant | 1 cup | 75mg |
| Tea | 1 cup | 50mg |
| Red Bull | 1 can | 80mg |
| Rockstar | 1 can | 160mg |
| Excedrin Migraine | 2 tabs | 130mg |
^Average caffeine content can vary[1][2]
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Pharmacology
- Half-life: 5 hours
- Metabolism: Liver CYP450
- Excretion: Urine
- Mechanism of Action: Adenosine receptor antagonist
Mechanism of Action
- Methylxanthine structure that antagonizes adenosine receptors
Indications by Condition
The following table is automatically generated from disease/condition pages across WikEM.
| Indication | Dose | Context | Route | Population |
|---|---|---|---|---|
| Post-lumbar puncture headache | 300mg PO x1, or 500mg IV in 1L NS over 1hr | Conservative management before blood patch | PO/IV | Adult |
See Also
References
- ↑ Food Standards Agency (2001) Statement on the Reproductive Effects of Caffeine. London: Food Standards Agency.
- ↑ Juliano LM and Griffiths RR. Caffeine. In Lowinson, J.H., Ruiz, P., Millman, R.B., Langrod, J.G. (Eds.). Substance Abuse: A Comprehensive Textbook, Fourth Edition. 2005. PP. 403-421. Baltimore: Lippincott, Williams, & Wilkins.