Sodium nitrite toxicity: Difference between revisions
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**It has many uses across multiple industries, including as a food additive
**It has many uses across multiple industries, including as a food additive
**[[Sodium nitrite]] also has some medical use as an antidote to certain toxidromes.
**[[Sodium nitrite]] also has some medical use as an antidote to certain toxidromes.
*Recent toxicology and suicidology literature has described a trend of suicides by poisoning with sodium nitrite.
*Recent toxicology and suicidology literature has described a trend of suicides by poisoning with sodium nitrite.<ref name="Nursing">Smith EM. Sodium nitrite suicide and social media influence. Nursing. 2023;53(12):44-47. doi:10.1097/01.NURSE.0000991568.99431.13</ref><ref name="SocialMedia">Smith EM. Sodium nitrite suicide and social media influence. Nursing. 2023;53(12):44-47. doi:10.1097/01.NURSE.0000991568.99431.13</ref><ref name="SysReview">Mazzini E, Feola A, Fracassi I, et al. Suicide by sodium nitrite ingestion: a systematic review. Forensic Sci Med Pathol. Published online August 30, 2025. doi:10.1007/s12024-025-01066-9</ref><ref name="Surveillance">Bloom J, Sharpe A, Nulman S, et al. Comparing Confirmed Sodium Nitrite Suicide Deaths With Poison Center Surveillance Estimates. JAMA Netw Open. 2024;7(9):e2434192. Published 2024 Sep 3. doi:10.1001/jamanetworkopen.2024.34192</ref><ref name="Reporting">Khan H, Barber C, Azrael D. Suicide by sodium nitrite poisoning: Findings from the National Violent Death Reporting System, 2018-2020. Suicide Life Threat Behav. 2024;54(2):310-316. doi:10.1111/sltb.13043</ref><ref name="DualReport">Yoon JC, Kim SE. Suicide attempt using sodium nitrite ordered on the internet: Two case reports. Medicine (Baltimore). 2022;101(28):e29355. Published 2022 Jul 15. doi:10.1097/MD.0000000000029355</ref><ref name="InternetOrder">Loiseau M, Matheux A, Sabini S, et al. Suicide of an adolescent girl with sodium nitrite ordered on the internet. J Forensic Sci. 2023;68(6):2200-2204. doi:10.1111/1556-4029.15350</ref>


==Clinical Features==
==Clinical Features==

Revision as of 18:53, 31 October 2025

Background

  • Sodium Nitrite is an inorganic compound composed of a sodium (Na) bonded to a nitrite (NO2) group[1]
    • High-purity sodium nitrite is a highly water-soluble, yellowish-white powder[1]
    • It has many uses across multiple industries, including as a food additive
    • Sodium nitrite also has some medical use as an antidote to certain toxidromes.
  • Recent toxicology and suicidology literature has described a trend of suicides by poisoning with sodium nitrite.[2][3][4][5][6][7][8]

Clinical Features

Differential Diagnosis

Evaluation

Workup

Diagnosis

Management

Disposition

See Also

External Links

References

  1. ↑ 1.0 1.1 https://en.wikipedia.org/wiki/Sodium_nitrite
  2. ↑ Smith EM. Sodium nitrite suicide and social media influence. Nursing. 2023;53(12):44-47. doi:10.1097/01.NURSE.0000991568.99431.13
  3. ↑ Smith EM. Sodium nitrite suicide and social media influence. Nursing. 2023;53(12):44-47. doi:10.1097/01.NURSE.0000991568.99431.13
  4. ↑ Mazzini E, Feola A, Fracassi I, et al. Suicide by sodium nitrite ingestion: a systematic review. Forensic Sci Med Pathol. Published online August 30, 2025. doi:10.1007/s12024-025-01066-9
  5. ↑ Bloom J, Sharpe A, Nulman S, et al. Comparing Confirmed Sodium Nitrite Suicide Deaths With Poison Center Surveillance Estimates. JAMA Netw Open. 2024;7(9):e2434192. Published 2024 Sep 3. doi:10.1001/jamanetworkopen.2024.34192
  6. ↑ Khan H, Barber C, Azrael D. Suicide by sodium nitrite poisoning: Findings from the National Violent Death Reporting System, 2018-2020. Suicide Life Threat Behav. 2024;54(2):310-316. doi:10.1111/sltb.13043
  7. ↑ Yoon JC, Kim SE. Suicide attempt using sodium nitrite ordered on the internet: Two case reports. Medicine (Baltimore). 2022;101(28):e29355. Published 2022 Jul 15. doi:10.1097/MD.0000000000029355
  8. ↑ Loiseau M, Matheux A, Sabini S, et al. Suicide of an adolescent girl with sodium nitrite ordered on the internet. J Forensic Sci. 2023;68(6):2200-2204. doi:10.1111/1556-4029.15350
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