Antihistamines: Difference between revisions
| Line 18: | Line 18: | ||
*[[Cimetidine]] | *[[Cimetidine]] | ||
*[[Famotidine]] | *[[Famotidine]] | ||
*[[Nizatidine]] | *[[Nizatidine]] | ||
*[[Ranitidine]] | *[[Ranitidine]] | ||
*[[Roxatidine]] | *[[Roxatidine]] | ||
==Indications== | ==Indications== | ||
Revision as of 21:17, 23 May 2015
Background
- Also known as histamine antagonists
- In common use, the term antihistamine refers only to compounds that inhibit action at the H1 receptor (and not H2, etc.).
Types
H1 antagonist
- Brompheniramine (Dimetane)
- Cetirizine (Zyrtec)
- Dimenhydrinate
- Diphenhydramine (Benadryl)
- Doxylamine
- Fexofenadine (Allegra)
- Hydroxyzine (Vistaril)
- Loratadine (Claritin)
- Meclozine
H2-receptor antagonists
Indications
- H1 antagonists
- H2 antagonists
Side Effects
- Sedation
- Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness
- Anticholinergic toxicity