Template:Streptococcal Pharyngitis Antibiotics: Difference between revisions
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'''[[Penicillin]] allergic (mild):<ref name=Shulman12>Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82</ref>''' | '''[[Penicillin]] allergic (mild):<ref name=Shulman12>Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82</ref>''' | ||
*[[Cephalexin]] 20 mg per kg PO BID (maximum 500 mg per dose) x 10 days | *[[Cephalexin]] 20 mg per kg PO BID (maximum 500 mg per dose) x 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref> | ||
*[[Cefadroxil]] 30 mg per kg PO QD (maximum 1 g daily) x 10 days | *[[Cefadroxil]] 30 mg per kg PO QD (maximum 1 g daily) x 10 days<ref>CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html</ref> | ||
'''[[Penicillin]] allergic (anaphylaxis):<ref name=Shulman12>Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82</ref>''' | '''[[Penicillin]] allergic (anaphylaxis):<ref name=Shulman12>Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82</ref>''' | ||
*[[Clindamycin]] 7.5mg/kg PO QID x 10d (child) or 450mg PO TID x 10d OR | *[[Clindamycin]] 7.5mg/kg PO QID x 10d (child) or 450mg PO TID x 10d OR | ||
*[[Azithromycin]] 12mg/kg QD (child) or 500mg on day 1; then 250mg on days 2-5 | *[[Azithromycin]] 12mg/kg QD (child) or 500mg on day 1; then 250mg on days 2-5 | ||
Revision as of 18:18, 28 January 2026
Treatment can be delayed for up to 9 days and still prevent major sequelae
Penicillin Options:
- Penicillin V 250mg PO BID x 10d (child) or 500mg BID x 10d (adolescent or adult)[1][2]
- Bicillin L-A <27 kg: 0.6 million units; ≥27 kg: 1.2 million units IM x 1 [1][3]
- Amoxicillin 50 mg/kg once daily (maximum = 1000 mg) for 10 days[4]
Penicillin allergic (mild):[1]
- Cephalexin 20 mg per kg PO BID (maximum 500 mg per dose) x 10 days[5]
- Cefadroxil 30 mg per kg PO QD (maximum 1 g daily) x 10 days[6]
Penicillin allergic (anaphylaxis):[1]
- Clindamycin 7.5mg/kg PO QID x 10d (child) or 450mg PO TID x 10d OR
- Azithromycin 12mg/kg QD (child) or 500mg on day 1; then 250mg on days 2-5
- ↑ 1.0 1.1 1.2 1.3 Shulman, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases 2012;55(10):1279–82
- ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
- ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
- ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
- ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html
- ↑ CDC Website, accessed 2026-28-01. https://www.cdc.gov/group-a-strep/hcp/clinical-guidance/strep-throat.html