Template:Appendicitis Antibiotics: Difference between revisions
(Add disease=Appendicitis parameter to AntibioticDose calls - fixes aggregation page display issue) |
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''Coverage should extend to [[E. coli|E. coli]], [[Klebsiella|Klebsiella]], [[Proteus|Proteus]], and [[Bacteroides|Bacteroides]] (an anaerobe)'' | |||
''Coverage should extend to [[ | |||
====Adult Simple Appendicitis==== | ====Adult Simple Appendicitis==== | ||
''Antibiotic prophylaxis should be coordinated with surgical consult'' | ''Antibiotic prophylaxis should be coordinated with surgical consult'' | ||
'''Options:''' | '''Options:''' | ||
*{{AntibioticDose|disease=Appendicitis|drug=Cefoxitin|dose=2g IV q6 hours|context=Adult Simple}} OR | *{{AntibioticDose|disease=Appendicitis|drug=Cefoxitin|dose=2g IV q6 hours|context=Adult Simple}} OR | ||
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====Pediatric Simple Appendicitis==== | ====Pediatric Simple Appendicitis==== | ||
'''Options:''' | '''Options:''' | ||
*{{AntibioticDose|disease=Appendicitis|drug=Cefoxitin|dose=40mg/kg IV q6 hours|context=Pediatric Simple|population=Pediatric}} | *{{AntibioticDose|disease=Appendicitis|drug=Cefoxitin|dose=40mg/kg IV q6 hours|context=Pediatric Simple|population=Pediatric}} | ||
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====Complicated Appendicitis==== | ====Complicated Appendicitis==== | ||
''Defined as perforation, abscess, or phlegmon'' | ''Defined as perforation, abscess, or phlegmon'' | ||
'''Options:''' | '''Options:''' | ||
*{{AntibioticDose|disease=Appendicitis|drug=Metronidazole|dose=500 mg IV q8hrs|context=Complicated}} + | *{{AntibioticDose|disease=Appendicitis|drug=Metronidazole|dose=500 mg IV q8hrs|context=Complicated}} + | ||
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*{{AntibioticDose|disease=Appendicitis|drug=Piperacillin/Tazobactam|dose=100 mg/kg (max 4.5g) IV q8hrs|context=Complicated}} | *{{AntibioticDose|disease=Appendicitis|drug=Piperacillin/Tazobactam|dose=100 mg/kg (max 4.5g) IV q8hrs|context=Complicated}} | ||
''Cautious use should be applied to use of [[ | ''Cautious use should be applied to use of [[fluoroquinolones|fluoroquinolones]] in complicated pediatric appendicitis due to the risk of tendon injury'' | ||
Revision as of 02:53, 20 March 2026
Coverage should extend to E. coli, Klebsiella, Proteus, and Bacteroides (an anaerobe)
Adult Simple Appendicitis
Antibiotic prophylaxis should be coordinated with surgical consult
Options:
- Cefoxitin 2g IV q6 hours OR
- Cefotetan 2g IV q12 hours OR
- Moxifloxacin 400mg IV once daily OR
- Ertapenem 1g IV once daily
Pediatric Simple Appendicitis
Options:
- Cefoxitin 40mg/kg IV q6 hours
- Cefotetan 40mg/kg IV q12 hours
- Gentamicin 2.5mg/kg IV q8hrs +
- Metronidazole 7.5mg/kg IV q6hrs OR
- Clindamycin 10mg/kg IV q8hrs
Complicated Appendicitis
Defined as perforation, abscess, or phlegmon
Options:
- Metronidazole 500 mg IV q8hrs +
- Cefepime 50 mg/kg IV q12hrs OR
- Ciprofloxacin 400 mg IV q12hrs OR
- Levofloxacin 750 mg IV q24hrs OR
- Aztreonam 30 mg/kg IV q8hrs
- Imipenem/Cilastatin 25 mg/kg IV q6hrs (max 500mg)
- Meropenem 20 mg/kg IV q8hrs (max 1g)
- Piperacillin/Tazobactam 100 mg/kg (max 4.5g) IV q8hrs
Cautious use should be applied to use of fluoroquinolones in complicated pediatric appendicitis due to the risk of tendon injury