Disulfiram effect: Difference between revisions
(new page) |
No edit summary |
||
| Line 1: | Line 1: | ||
==Background== | ==Background== | ||
The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus). Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol | The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus). Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to [[Ethanol|ethanol]]. Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a "hangover" are felt immediately after alcohol is consumed. The disulfiram effect refers to similar symptoms seen when other medications are mixed with ethanol. | ||
==Medications with Similar Effects== | ==Medications with Similar Effects== | ||
* Antibiotics ([[Metronidazole|metronidazole]], cephalosporins (cefotetan) | * Antibiotics ([[Metronidazole|metronidazole]], [[Cephalosporins|cephalosporins]] (cefotetan)) | ||
* Antifungals ([[Griseofulvin]]) | * Antifungals ([[Griseofulvin]]) | ||
| Line 9: | Line 9: | ||
Care is primarily supportive. | Care is primarily supportive. | ||
[[ | [[Category:Drugs]] | ||
Revision as of 06:02, 6 August 2015
Background
The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus). Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol. Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a "hangover" are felt immediately after alcohol is consumed. The disulfiram effect refers to similar symptoms seen when other medications are mixed with ethanol.
Medications with Similar Effects
- Antibiotics (metronidazole, cephalosporins (cefotetan))
- Antifungals (Griseofulvin)
Treatment
Care is primarily supportive.