Furosemide: Difference between revisions
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*Hypercalcemia: 120 mg/day PO divided QDAY - TID | *Hypercalcemia: 120 mg/day PO divided QDAY - TID | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
* Hypercalcemia: 25-50 mg IV q4h | *Hypercalcemia: 25-50 mg IV q4h | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:C | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]:C | ||
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*urinary frequency | *urinary frequency | ||
*dizziness | *dizziness | ||
* nausea/vomiting | *nausea/vomiting | ||
* weakness | *weakness | ||
*muscle cramping | *muscle cramping | ||
*hypokalemia | *hypokalemia | ||
Revision as of 03:42, 6 July 2016
General
- Type: Diuretic
- Dosage Forms:20, 40, 80
- Common Trade Names: Lasix
Adult Dosing
- HTN: 10-40 mg PO QDAY-BID, max 600 mg/day
- Hypercalcemia: 120 mg/day PO divided QDAY - TID
Pediatric Dosing
- Hypercalcemia: 25-50 mg IV q4h
Special Populations
- Pregnancy Rating:C
- Lactation: safety unknown
- Renal Dosing
- Adult: no adjustment, contraindicated in anuria
- Pediatric: no adjustment, contraindicated in anuria
- Hepatic Dosing
- Adult: not defined
- Pediatric: not defined
Contraindications
- Allergy to class/drug
- anuria
- electrolyte imbalances
Adverse Reactions
Serious
- hypokalemia
- metabolic alkalosis
- hypovolemia
- ototoxicity
- hemolytic anemia
- vasculitis
- steven-johnson syndrome
- pancreatitis
- eosinophilia
Common
- urinary frequency
- dizziness
- nausea/vomiting
- weakness
- muscle cramping
- hypokalemia
- hypomagnesemia
- blurred vision
- diarrhea
- hyperglycemia
- hyperuricemia
- tinnitus
Pharmacology
- Half-life: 30-60 min
- Metabolism: liver minimally
- Excretion: urine
- Mechanism of Action: inhibits loop of henle and proximal and distal convoluted tubule sodium and chloride resorption