Loperamide toxicity: Difference between revisions
No edit summary |
|||
| Line 10: | Line 10: | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
{{Sedatve/hypnotic toxicity types}} | |||
==Evaluation== | ==Evaluation== | ||
Revision as of 07:18, 14 August 2017
Background
- Increasing reports of intentional overdose at very high doses either for euphoric effects or to attenuate symptoms of opioid withdrawal[1]
Clinical Features
- May have features of conventional opioid toxicity
Loperamide-induced cardiac toxicity[2]
- Often young
- May present in cardiac arrest or with recurrent syncope in conjunction with ECG agnormalities
Differential Diagnosis
Sedative/hypnotic toxicity
- Absinthe
- Barbiturates
- Benzodiazepines
- Chloral hydrate
- Gamma hydroxybutyrate (GHB)
- Baclofen toxicity
- Opioids
- Toxic alcohols
- Xylazine toxicity