Fidaxomicin: Difference between revisions
ClaireLewis (talk | contribs) (Created page with "==Administration== *Type: Macrolide antibiotic *Dosage Forms: *Routes of Administration: PO *Common Trade Names: ==Adult Dosing== *C.diff diarrhea: 200mg PO BID x 10...") |
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==Adult Dosing== | ==Adult Dosing== | ||
*[[C.diff]] diarrhea: 200mg PO BID x 10d | *[[C. diff]] diarrhea: 200mg PO BID x 10d | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 01:46, 27 January 2019
Administration
- Type: Macrolide antibiotic
- Dosage Forms:
- Routes of Administration: PO
- Common Trade Names:
Adult Dosing
- C. diff diarrhea: 200mg PO BID x 10d
Pediatric Dosing
Safety/efficacy not established
Special Populations
Pregnancy Rating
- Category B
Lactation risk
- Infant risk cannot be ruled out
Renal Dosing
- No adjustment
Hepatic Dosing
- Not established
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: ~12h
- Metabolism: Intestinal
- Excretion: Fecal
Mechanism of Action
- Macrolide: inhibits RNA polymerases primarily against clostridia species