Myalgia: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
*Infection: | *Infection: | ||
**Viral infection (e.g. [[Influenza | **Viral infection (e.g. [[Influenza]]) | ||
**Bacterial infection | **Bacterial infection | ||
**Spirochete infection (E.g. [[Dengue fever]]; [[Trichinella | **Spirochete infection (E.g. [[Dengue fever]]; [[Trichinella]]) | ||
*Drugs: | *Drugs: | ||
**Statins | **[[Statins]] | ||
**Bisphosphonates | **Bisphosphonates | ||
** | **Corticosteroids | ||
** | **Ciprofloxacin | ||
** | **Clofibrate | ||
** | **Colchicine | ||
** | **Chloroquine | ||
** | **Emetine | ||
** | **Aminocaproic acid | ||
** | **Zidovudine | ||
** | **Bretylium | ||
** | **Penicillamine | ||
** | **Drugs causing [[hypokalemia]] | ||
*Metabolic disorders: | *Metabolic disorders: | ||
**Vitamin D deficiency | **[[Vitamin D deficiency]] | ||
**Mitochondrial myopathy | **Mitochondrial myopathy | ||
**Scurvy | **[[Scurvy]] | ||
**Osteomalacia | **Osteomalacia | ||
*Fibromyalgia | *Fibromyalgia | ||
*Endocrine: | *Endocrine: | ||
** | **[[Hypothyroidism]] | ||
** | **[[Hyperthyroidism]] | ||
**Cushing’s syndrome | **[[Cushing’s syndrome]] | ||
**Adrenal insufficiency | **[[Adrenal insufficiency]] | ||
**Hyperparathyroidism | **[[Hyperparathyroidism]] | ||
*Polymyalgia rheumatica | *[[Polymyalgia rheumatica]] | ||
*Rhabdomyolysis | *[Rhabdomyolysis]] | ||
*Myositis ( | *[[Myositis]] (e.g, polymyositis, dermatomyositis) | ||
*Systemic lupus erythematosus | *[[Systemic lupus erythematosus]] | ||
*Rheumatoid arthritis | *[Rheumatoid arthritis]] | ||
*Inclusion body myositis | *Inclusion body myositis | ||
*Sarcoidosis | *[[Sarcoidosis]] | ||
*Scleroderma | *[[Scleroderma]] | ||
*Sjögren’s syndrome | *[[Sjögren’s syndrome]] | ||
*Psychiatric (e.g. somatic manifestations of depression) | *Psychiatric (e.g. somatic manifestations of depression) | ||
*Domestic abuse | *[[Domestic abuse]] | ||
*Lyme disease | *[[Crush injury]] | ||
*[[Lyme disease]] | |||
*Ehlers Danlos (Hypermobility syndrome) | *Ehlers Danlos (Hypermobility syndrome) | ||
*HIV myopathy | *[HIV]] myopathy | ||
*Hypophosphatemia | *[[Hypophosphatemia]] | ||
*Hypokalemia | *[[Hypokalemia]] | ||
*Hypothermia | *[[Hypothermia]] | ||
*Prolonged immobility | *Prolonged immobility | ||
*Strenuous exercise (overuse) or heat stroke | *Strenuous exercise (overuse) or [[heat stroke]] | ||
*Seizure | *[[Seizure]] | ||
*Severe volume contraction | *Severe volume contraction | ||
*Alcoholism | *[Alcoholism]] | ||
*Muscular dystrophy | *Muscular dystrophy | ||
*Compartment syndrome; Muscle infarction | **Duchenne | ||
**Becker | |||
**limb-girdle | |||
**facioscapulohumeral | |||
**Myotonic dystrophy | |||
**Myotonia congenita | |||
*[[Compartment syndrome]]; Muscle infarction | |||
*Neuropathic | *Neuropathic | ||
*Chronic fatigue syndrome | *Chronic fatigue syndrome | ||
*Vasculitis | *Vasculitis | ||
*Sarcocystosis | *[[Sarcocystosis]] | ||
*Spinal stenosis | *[[Spinal stenosis]] | ||
*Diabetic lumbosacral plexopathy | *Diabetic lumbosacral plexopathy | ||
Revision as of 00:46, 2 April 2019
Background
Clinical Features
Differential Diagnosis
- Infection:
- Viral infection (e.g. Influenza)
- Bacterial infection
- Spirochete infection (E.g. Dengue fever; Trichinella)
- Drugs:
- Statins
- Bisphosphonates
- Corticosteroids
- Ciprofloxacin
- Clofibrate
- Colchicine
- Chloroquine
- Emetine
- Aminocaproic acid
- Zidovudine
- Bretylium
- Penicillamine
- Drugs causing hypokalemia
- Metabolic disorders:
- Vitamin D deficiency
- Mitochondrial myopathy
- Scurvy
- Osteomalacia
- Fibromyalgia
- Endocrine:
- Polymyalgia rheumatica
- [Rhabdomyolysis]]
- Myositis (e.g, polymyositis, dermatomyositis)
- Systemic lupus erythematosus
- [Rheumatoid arthritis]]
- Inclusion body myositis
- Sarcoidosis
- Scleroderma
- Sjögren’s syndrome
- Psychiatric (e.g. somatic manifestations of depression)
- Domestic abuse
- Crush injury
- Lyme disease
- Ehlers Danlos (Hypermobility syndrome)
- [HIV]] myopathy
- Hypophosphatemia
- Hypokalemia
- Hypothermia
- Prolonged immobility
- Strenuous exercise (overuse) or heat stroke
- Seizure
- Severe volume contraction
- [Alcoholism]]
- Muscular dystrophy
- Duchenne
- Becker
- limb-girdle
- facioscapulohumeral
- Myotonic dystrophy
- Myotonia congenita
- Compartment syndrome; Muscle infarction
- Neuropathic
- Chronic fatigue syndrome
- Vasculitis
- Sarcocystosis
- Spinal stenosis
- Diabetic lumbosacral plexopathy
Evaluation
- Myalgias can be divided into diffuse (systemic) myalgias vs. Localized myalgias.
- Muscle pain can come from Rhabdomyolysis, Myositis, or Myopathy.