Template:Cholecystitis Antibiotics: Difference between revisions
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''Most often isolated organisms are [[Escherichia coli]], [[Klebsiella pneumonia]], and [[anaerobes]], especially [[Bacteroides fragilis]] | ''Most often isolated organisms are [[Escherichia coli]], [[Klebsiella pneumonia]], and [[anaerobes]], especially [[Bacteroides fragilis]]'' | ||
====Uncomplicated Cholecystitis==== | ====Uncomplicated Cholecystitis==== | ||
''Pathogenicity of [[Enterococci]] remains unclear and specific coverage is not routinely suggested for community-acquired infections''<ref>Ansaloni L, et al. 2016 WSES guidelines on acute calculous cholecystitis. World Journal of Surgery. (2016) 11:25. DOI 10.1186/s13017-016-0082-5</ref> | |||
*[[Ertapenem]] 1g IV once daily OR | *[[Ertapenem]] 1g IV once daily OR | ||
*[[Metronidazole]] 500mg IV q8hrs PLUS | *[[Metronidazole]] 500mg IV q8hrs PLUS | ||
Revision as of 02:45, 3 April 2019
Most often isolated organisms are Escherichia coli, Klebsiella pneumonia, and anaerobes, especially Bacteroides fragilis
Uncomplicated Cholecystitis
Pathogenicity of Enterococci remains unclear and specific coverage is not routinely suggested for community-acquired infections[1]
- Ertapenem 1g IV once daily OR
- Metronidazole 500mg IV q8hrs PLUS
- Ciprofloxacin 400mg IV q12 hrs OR
- Levofloxacin 750mg IV q24hrs OR
- Ceftriaxone 1g IV q24hrs
Complicated
Complicated disease such as severe sepsis or hemodynamic instability
- Vancomycin 15-20mg/kg PLUS any of the following options
Options:
- Metronidazole 500mg IV q8hrs PLUS Ciprofloxacin 400mg IV q12hrs
- Piperacillin/Tazobactam 4.5g IV q8hrs
- Imipenem/Cilastin 500mg IV q6hrs
- Doripenem 500mg IV q8hrs
- Meropenem 1g IV q8hrs
- ↑ Ansaloni L, et al. 2016 WSES guidelines on acute calculous cholecystitis. World Journal of Surgery. (2016) 11:25. DOI 10.1186/s13017-016-0082-5