Xylazine toxicity: Difference between revisions
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==Clinical Features== | ==Clinical Features== | ||
*[[Bradycardia]] | *[[Bradycardia]] | ||
* | *Respiratory depression | ||
*[[Hypotension]] | *[[Hypotension]] | ||
Revision as of 19:46, 21 August 2019
Background
- Analogue of clonidine and agonist at alpha 2 adrenergic receptor
- Veterinary sedative, anesthetic, analgesic, and muscle relaxant
- Human drug of abuse, usually as drug adulterant
Clinical Features
- Bradycardia
- Respiratory depression
- Hypotension
Differential Diagnosis
- See Bradycardia, Hypotension
Sedative/hypnotic toxicity
- Absinthe
- Barbiturates
- Benzodiazepines
- Chloral hydrate
- Gamma hydroxybutyrate (GHB)
- Baclofen toxicity
- Opioids
- Toxic alcohols
- Xylazine toxicity
Evaluation
- Evaluate for alternate etiologies
- Clinical diagnosis
Management
- Supportive: address airway/respiratory drive/blood pressure, atropine for bradycardia
Disposition
- Admit if not back to baseline