Hydrops fetalis: Difference between revisions

(Text replacement - "OR" to "'''OR'''")
No edit summary
 
Line 5: Line 5:


==Clinical Features==
==Clinical Features==
*Edema is typically located in:
*Occurs during gestation, may be maternally asymptomatic or present as [[spontaneous abortion]], or patient (mother) may have sings/symptoms of pathology that caused hydrops
*Fetal/neonatal edema is typically located in:
**Subcutaneous tissue/scalp
**Subcutaneous tissue/scalp
**Pleura (pleural effusion)
**Pleura ([[pleural effusion]])
**Pericardium (pericardial effusion)
**Pericardium ([[pericardial effusion]])
**Abdomen (ascites)
**Abdomen ([[ascites]])


==Immune==
==Complications==
*Spontaneous abortions
*Poor fetal outcomes
 
==Causes==
===Immune===
*Rh disease
*Rh disease
**RhD-negative mothers during pregnancy and/or within 72 hours of the delivery '''OR''' vaginal bleeding
**RhD-negative mothers during pregnancy and/or within 72 hours of the delivery '''OR''' vaginal bleeding
**Prevention with administration of anti-D IgG (Rho(D) Immune Globulin) injections  
**Prevention with administration of anti-D IgG ([[Rho(D) Immune Globulin]]) injections  
 
===Non-Immune===
==Non-Immune==
*Iron deficiency [[anemia]]
*Iron Deficiency Anemia
*[[Parvovirus B19]] (Fifth's Disease)
*Parvovirus B19 (Fifth's Disease)
*[[CMV]]
*CMV
*[[Syphilis]]
*Maternal Syphilis


==Evaluation==
==Evaluation==
*Ultrasound screening
*[[pelvic ultrasound|Ultrasound]] screening
 
==Complications==
*Spontaneous Abortions
*Poor Fetal Outcomes


==Management==
==Management==

Latest revision as of 19:44, 3 October 2019

Background

  • Accumulation of edema in at least two fetal compartments
  • Usually stems from fetal anemia
  • Immune vs Non-Immune

Clinical Features

  • Occurs during gestation, may be maternally asymptomatic or present as spontaneous abortion, or patient (mother) may have sings/symptoms of pathology that caused hydrops
  • Fetal/neonatal edema is typically located in:

Complications

  • Spontaneous abortions
  • Poor fetal outcomes

Causes

Immune

  • Rh disease
    • RhD-negative mothers during pregnancy and/or within 72 hours of the delivery OR vaginal bleeding
    • Prevention with administration of anti-D IgG (Rho(D) Immune Globulin) injections

Non-Immune

Evaluation

Management

  • OBGYN Consultation/Referral
  • Rh Status
  • Iron for all pregnant women

Also See

References

  • Uptodate
  • Bellini C, Hennekam RC. Non-immune hydrops fetalis: a short review of etiology and pathophysiology. Am J Med Genet A 2012; 158A:597.
  • Haile-Mariam T, Polis MA: Viral Illnesses, in Marx JA, Hockberger RS, Walls RM, et al (eds): Emergency Medicine: Concepts and Clinical Practice, ed. 7. St. Louis, Mosby, Inc., 2010, (Ch) 128: p.1712.