Q fever: Difference between revisions

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* Described in 1937: occupational disease of abattoir workers (manage animals before and after slaughtering process) and dairy farmers
* Described in 1937: occupational disease of abattoir workers (manage animals before and after slaughtering process) and dairy farmers
* Caused by Coxiella burnetii
* Caused by Coxiella burnetii
* Obligate intracellular bacteria morphologically similar to Rickettsia
** Obligate intracellular bacteria morphologically similar to Rickettsia
* Reservoirs include cattle, goat, sheep, and ticks (Dermacentor andersoni)
** Reservoirs include cattle, goat, sheep, and ticks (Dermacentor andersoni)
* CDC: category B biologic warfare agent due to its inhaled infectivity
* CDC: category B biologic warfare agent due to its inhaled infectivity
* Worldwide disease
* Worldwide disease

Revision as of 18:12, 17 October 2014

Background

  • Described in 1937: occupational disease of abattoir workers (manage animals before and after slaughtering process) and dairy farmers
  • Caused by Coxiella burnetii
    • Obligate intracellular bacteria morphologically similar to Rickettsia
    • Reservoirs include cattle, goat, sheep, and ticks (Dermacentor andersoni)
  • CDC: category B biologic warfare agent due to its inhaled infectivity
  • Worldwide disease

Clinical Features

  • Symptoms usually develop within 2-3 weeks, although up to half of those infected may not show symptoms
    • high fevers (up to 104-105°F)
    • severe headache
    • general malaise
    • myalgias
    • chills/sweats
    • non-productive cough
    • nausea/vomiting
    • diarrhea
    • abdominal pain
    • chest pain
  • Complications include pneumonia, granulomatous hepatitis (inflammation of the liver), myocarditis (inflammation of the heart tissue), and central nervous system complications.
  • Endocarditis is the major form of chronic disease
  • Infection in pregnancy is more likely to be asymptomatic, but often results in chronic Q fever and obstetrical complications

Differential Diagnosis

Fever in traveler

Workup

Management

Disposition

See Also

External Links

Sources