Neonatal jaundice: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
#Isoimmune hemolytic disease | #Isoimmune hemolytic disease | ||
#G6PD deficiency | #G6PD deficiency | ||
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#Sepsis | #Sepsis | ||
#Acidosis | #Acidosis | ||
== Diagnosis == | == Diagnosis == | ||
#Direct (conjugated, post- liver obstructive) | #Direct (conjugated, post- liver obstructive) | ||
##congenital biliary atresia | ##congenital biliary atresia | ||
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==Work-Up== | ==Work-Up== | ||
#Tbil | #Tbil/Dbil | ||
#CBC (for hemolytic anemia) | #CBC (for hemolytic anemia) | ||
#Coombs or T&S (mom & baby) | #Coombs or T&S (mom & baby) | ||
Revision as of 22:31, 13 June 2011
Risk Factors
- Isoimmune hemolytic disease
- G6PD deficiency
- Asphyxia
- Significant lethargy
- Temperature instability
- Sepsis
- Acidosis
Diagnosis
- Direct (conjugated, post- liver obstructive)
- congenital biliary atresia
- neuroblastoma
- cholesterol cysts
- Cellular
- hepatitis
- galactosemia
- sepsis
- TORCHS
- tyrosinemia
- alpha 1 antitrypsis deficiency
- Indirect (unconjugated, pre-liver)
- sepsis
- hypotension
- rH/ ABO incompatibility
Work-Up
- Tbil/Dbil
- CBC (for hemolytic anemia)
- Coombs or T&S (mom & baby)
- ?blood resorption
- ?septic
- Decreased gastric motility
- Physiologic/breast milk (none @ birth presents 1st week)
Phototherapy Guidelines
| Age | Low | Med | High |
| Birth | 7.0 | 5.0 | 4.0 |
| 24h | 11.5 | 9.0 | 8.0 |
| 48h | 15 | 14 | 10 |
| 72h | 17.5 | 15 | 14 |
| 96h | 20 | 17.5 |
14.5 |
| 5+day | 21 | 17.5 | 15 |
Low Risk: >=38wk + no risk factors
Med Risk: (>=38wk + risk factors) or (35-37 wk and no risk factors)
High Risk: 35-37wk + risk factors
Source
UpToDate