Mediastinitis: Difference between revisions

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==Background==
==Background==
* A serious infection of the mediastinum with significant morbidity and mortality<ref>Infections of the mediastinum.
* Inflammation of the mediastinum
SB  - Thorac Surg Clin 2009 Feb; PMID 19288819 </ref> and generally requires surgery
**Commonly caused by esophageal rupture or perforation
**Typically caused by infection
***Streptococcus and Bacteroides
**Can be traumatic (swallowed razor blades, etc)


==Clinical Features==
==Clinical Features==
* [[Chest Pain (DDx)|Chest Pain]]
*Fever
*Dyspnea
*Chest pain
*Neck pain and swelling
**Crepitus
* Signs of [[Sepsis]]
* Signs of [[Sepsis]]
* Hamman sign on auscultation of precordium (crunch heard during systole)
* Hamman sign on auscultation of precordium (crunch heard during systole)


==Etiology==
==Etiology==
* Prior cardiovascular surgery (most common cause)
* Prior cardiovascular surgery (most common cause)<ref>Infections of the mediastinum. SB  - Thorac Surg Clin 2009 Feb; PMID 19288819 </ref>
* [[Esophageal Perforation|Esophageal rupture (Boerhaave Syndrome)]]
* [[Esophageal Perforation|Esophageal rupture (Boerhaave Syndrome)]]
* [[Ludwig Angina]]
* [[Ludwig Angina]]
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** Gram Stain
** Gram Stain
** Cultures of mediastinal pacing wires
** Cultures of mediastinal pacing wires
*CXR - often first modality
**Typically reveals subcutaneous emphysema, widening of the mediastinum and pleural effusions
* CT if diagnosis in doubt
* CT if diagnosis in doubt


==Management==
==Management==
*Airway intact?
* ''Patients with mediastinitis emergently require surgery''
* ''Patients with mediastinitis emergently require surgery''
**Consult
***CT Surgery for repair
***ENT if upper neck area
***GI for possible endoscopy
* Start broad-spectrum antibiotics to include Pseudomonal coverage<ref>El Oakley, RM et al. Postoperative mediastinitis: classification and management. Ann Thorac Surg. 1996. PMID 8619682</ref>
* Start broad-spectrum antibiotics to include Pseudomonal coverage<ref>El Oakley, RM et al. Postoperative mediastinitis: classification and management. Ann Thorac Surg. 1996. PMID 8619682</ref>


==Disposition==
==Disposition==
* Admit
* Admit
==See Also==
==See Also==
*[[Pneumomediastinum]]
*[[Pneumomediastinum]]

Revision as of 15:54, 2 February 2015

Background

  • Inflammation of the mediastinum
    • Commonly caused by esophageal rupture or perforation
    • Typically caused by infection
      • Streptococcus and Bacteroides
    • Can be traumatic (swallowed razor blades, etc)

Clinical Features

  • Fever
  • Dyspnea
  • Chest pain
  • Neck pain and swelling
    • Crepitus
  • Signs of Sepsis
  • Hamman sign on auscultation of precordium (crunch heard during systole)

Etiology

Workup

  • Septic workup to include:
    • CBC
    • Blood cultures
    • Gram Stain
    • Cultures of mediastinal pacing wires
  • CXR - often first modality
    • Typically reveals subcutaneous emphysema, widening of the mediastinum and pleural effusions
  • CT if diagnosis in doubt

Management

  • Airway intact?
  • Patients with mediastinitis emergently require surgery
    • Consult
      • CT Surgery for repair
      • ENT if upper neck area
      • GI for possible endoscopy
  • Start broad-spectrum antibiotics to include Pseudomonal coverage[2]

Disposition

  • Admit

See Also

Sources

  1. Infections of the mediastinum. SB - Thorac Surg Clin 2009 Feb; PMID 19288819
  2. El Oakley, RM et al. Postoperative mediastinitis: classification and management. Ann Thorac Surg. 1996. PMID 8619682

Medscape: Mediastinitis Treatment & Managemen. Mueller DK, et al.