Antihistamines: Difference between revisions
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==Background== | |||
*Also known as histamine antagonists | |||
*In common use, the term antihistamine refers only to compounds that inhibit action at the H<sub>1</sub> receptor (and not H<sub>2</sub>, etc.). | |||
==Types== | |||
===H1 antagonist=== | |||
*[[Brompheniramine]] (Dimetane) | |||
*[[Cetirizine]] (Zyrtec) | |||
*[[Dimenhydrinate]] | |||
*[[Diphenhydramine]] ([[Benadryl]]) | |||
*[[Doxylamine]] | |||
*[[Fexofenadine]] (Allegra) | |||
*[[Hydroxyzine]] (Vistaril) | |||
*[[Loratadine]] (Claritin) | |||
*[[Meclozine]] | |||
===H<sub>2</sub>-receptor antagonists=== | |||
*[[Cimetidine]] | |||
*[[Famotidine]] | |||
*[[Lafutidine]] | |||
*[[Nizatidine]] | |||
*[[Ranitidine]] | |||
*[[Roxatidine]] | |||
*[[Tiotidine]] | |||
==Indications== | |||
*H<sub>1</sub> antagonists | |||
**[[Allergic reactions]] | |||
**[[Insomnia]] | |||
**[[Vertigo]] | |||
*H<sub>2</sub> antagonists | |||
**[[GERD]]/[[peptic ulcers]] | |||
**[[Alergic reactions]] | |||
==Side Effects== | |||
*Sedation | |||
**Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness | |||
==See Also== | ==See Also== | ||
*[[Anticholinergic toxicity]] | *[[Anticholinergic toxicity]] | ||
==References== | |||
<references/> | |||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 20:57, 23 May 2015
Background
- Also known as histamine antagonists
- In common use, the term antihistamine refers only to compounds that inhibit action at the H1 receptor (and not H2, etc.).
Types
H1 antagonist
- Brompheniramine (Dimetane)
- Cetirizine (Zyrtec)
- Dimenhydrinate
- Diphenhydramine (Benadryl)
- Doxylamine
- Fexofenadine (Allegra)
- Hydroxyzine (Vistaril)
- Loratadine (Claritin)
- Meclozine
H2-receptor antagonists
Indications
- H1 antagonists
- H2 antagonists
Side Effects
- Sedation
- Second-generation antihistamines cross the blood–brain barrier to a much lower degree (therefore are less sedating), however high doses can still induce the drowsiness
