Phenobarbital: Difference between revisions
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*[[Alcohol withdrawal]] / Delirium Tremens | *[[Alcohol withdrawal]] / Delirium Tremens | ||
**130-260 mg IV q15-20 min <ref> Rosenson J, Clements C, Simon B, Vieaux J, Graffman S, Vahidnia F, Cisse B, Lam J, Alter H: Phenobarbital for acute alcohol withdrawal: a prospective randomized double-blind placebo-controlled study. J Emerg Med. 2013 Mar;44(3):592-598.e2. Epub 2012 Sep 19. </ref> | **130-260 mg IV q15-20 min <ref> Rosenson J, Clements C, Simon B, Vieaux J, Graffman S, Vahidnia F, Cisse B, Lam J, Alter H: Phenobarbital for acute alcohol withdrawal: a prospective randomized double-blind placebo-controlled study. J Emerg Med. 2013 Mar;44(3):592-598.e2. Epub 2012 Sep 19. </ref> | ||
*Seizures, maintenance tx | |||
**50-100 mg bid-tid | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 19:02, 26 May 2015
General
- Type: Anticonvulsant, barbiturate, barbituates
- Dosage Forms
- 65 mg/mL injection
- 20 mg/5 mL oral solution
- 15, 16.2, 30, 32.4, 60, 64.8, 97.2, 100 mg tab
Adult Dosing
- Status epilepticus
- 20 mg/kg, infuse at 50-100 mg/min
- May repeat once after 10 minutes with additional 5-10 mg/kg
- Alcohol withdrawal / Delirium Tremens
- 130-260 mg IV q15-20 min [1]
- Seizures, maintenance tx
- 50-100 mg bid-tid
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Sources
- ↑ Rosenson J, Clements C, Simon B, Vieaux J, Graffman S, Vahidnia F, Cisse B, Lam J, Alter H: Phenobarbital for acute alcohol withdrawal: a prospective randomized double-blind placebo-controlled study. J Emerg Med. 2013 Mar;44(3):592-598.e2. Epub 2012 Sep 19.