Mebendazole: Difference between revisions
ClaireLewis (talk | contribs) |
(Replace manual dosing with dynamic SMW tables) |
||
| Line 6: | Line 6: | ||
==Adult Dosing== | ==Adult Dosing== | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Mebendazole]] [[Has Population::Adult]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===Indications by Disease=== | |||
{{#ask: [[Has DrugName::Mebendazole]] [[Has Population::Pediatric]] | |||
|?Treats disease=Disease | |||
|?Has Dose=Dose | |||
|?Has Context=Context | |||
|format=table | |||
|limit=50 | |||
|mainlabel=- | |||
|headers=show | |||
|sort=Treats disease | |||
}} | |||
==Special Populations== | ==Special Populations== | ||
Revision as of 01:54, 20 March 2026
Administration
- Type: Antiparasitic (used to treat nematodes)
- Dosage Forms: Tablet 100mg
- Routes of Administration: Oral
- Common Trade Names: Emverm
Adult Dosing
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Enterobius | 100mg PO once then repeat in 2 weeks | Adult |
Pediatric Dosing
Indications by Disease
| Disease | Dose | Context |
|---|---|---|
| Enterobius | 100mg PO once then repeat in 2 weeks | Pediatric 2 years or older |
Special Populations
- Pregnancy Rating: C
- Lactation risk: infant risk cannot be ruled out
- Renal dosing: no adjustment
- Hepatic impairment: may need dose reduction
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Agranulocytosis
- Hepatitis
- Seizure
- Angioedema
Common
- Abdominal pain, diarrhea
Pharmacology
- Half-life: 0.8-11.5h
- Metabolism: Hepatic
- Excretion: Fecal
Mechanism of Action
- Causes parasitic microtubules to degenerate, inhibiting glucose uptake and glycogen storage
