DKA

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• Diabetic ketoacidosis

📊 Corrected Sodium for Hyperglycemia Calculator [show]

Corrected Sodium

Corrected Sodium for Hyperglycemia

Parameter	Value
Measured Sodium (mEq/L)
Serum Glucose (mg/dL)
Results
Corrected Na⁺ (Katz, 1.6 mEq per 100 mg/dL)	mEq/L
Corrected Na⁺ (Hillier, 2.4 mEq per 100 mg/dL)	mEq/L

References

Katz MA. Hyperglycemia-induced hyponatremia — calculation of expected serum sodium depression. N Engl J Med. 1973;289(16):843-844. PMID 4763428. Hillier TA, Abbott RD, Barrett EJ. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med. 1999;106(4):399-403. PMID 10225241. Classic formula (Katz): Corrected Na = Measured Na + 1.6 × (Glucose − 100) / 100 Revised formula (Hillier): Corrected Na = Measured Na + 2.4 × (Glucose − 100) / 100 (preferred when glucose >400)

📊 Anion Gap Calculator [show]

Anion Gap

Anion Gap Calculator

Parameter	Value
Sodium (Na⁺) mEq/L
Chloride (Cl⁻) mEq/L
Bicarbonate (HCO₃⁻) mEq/L
Albumin (g/dL) — optional, for correction
Results
Anion Gap	mEq/L
Corrected AG (for albumin)	mEq/L
Delta-Delta Ratio (ΔAG / ΔHCO₃)

Interpretation
AG <12	Normal anion gap — Consider non-AG metabolic acidosis (HARDUPS mnemonic).
AG ≥12	Elevated anion gap — Consider MUDPILES: Methanol, Uremia, DKA, Propylene glycol, Isoniazid/Iron, Lactic acidosis, Ethylene glycol, Salicylates.
Delta-Delta Ratio
<1	Concurrent non-AG metabolic acidosis (mixed).
1–2	Pure anion gap metabolic acidosis.
>2	Concurrent metabolic alkalosis (or pre-existing elevated HCO₃).

References
Kraut JA, Madias NE. Serum anion gap: its uses and limitations in clinical medicine. Clin J Am Soc Nephrol. 2007;2:162-174. PMID 17699401. Fenves AZ et al. Increased anion gap metabolic acidosis as a result of 5-oxoproline (pyroglutamic acid). Proc (Bayl Univ Med Cent). 2006;19:364-367.