Disulfiram effect: Difference between revisions

Revision as of 05:16, 9 August 2015

Disulfiram (Trade names: Antabuse, Antabus) - causes an acute reaction in the presence of ethanol.
- Works by inhibiting acetaldehyde dehydrogenase → buildup of acetaldehyde → unpleasant effects.
- Designed to assist in alcohol cessation.

Authors:

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 ==Background==
-The disulfiram effect refers to medication adverse effect that are similar to those seen with disulfiram (trade names Antabuse, Antabus).  Disulfiram is a drug that is used to support the treatment of chronic alcoholism by producing an acute sensitivity to [[Ethanol|ethanol]]. Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means many of the effects of a "hangover" are felt immediately after alcohol is consumed.  The disulfiram effect refers to similar symptoms seen when other medications are mixed with ethanol.
+*Disulfiram (Trade names: '''Antabuse''', '''Antabus''') - causes an acute reaction in the presence of [[ethanol]].
+**Works by inhibiting acetaldehyde dehydrogenase → buildup of acetaldehyde → unpleasant effects.
+**Designed to assist in alcohol cessation.
+==Clinical Features==
+==Differential Diagnosis==
+==Diagnosis==
+*Clinical diagnosis
 ==Medications with Similar Effects==
@@ Line 6: / Line 17: @@
 * Antifungals ([[Griseofulvin]])
-==Treatment==
+==Management==
-Care is primarily supportive.
+*Supportive care
+==Disposition==
+==See Also==
+[[Ethanol toxicity]]
+==References==
+<References/>
 [[Category:Drugs]]
+[[Category:Tox]]