Clozapine: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
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**Pediatric | **Pediatric | ||
==Indications== | |||
*Controls positive and negative symptoms of psychotic disorders | |||
*Used for schizophrenia | |||
*Off label use: | |||
**Bipolar disorder | |||
**Borderline personality disorder | |||
==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
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*[[Antipsychotic Medications]] | *[[Antipsychotic Medications]] | ||
== | ==References== | ||
<references/> | <references/> | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
[[Category:Psych]] | [[Category:Psych]] | ||
Revision as of 03:38, 29 August 2015
General
- Type: Atypical antipsychotic
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Indications
- Controls positive and negative symptoms of psychotic disorders
- Used for schizophrenia
- Off label use:
- Bipolar disorder
- Borderline personality disorder
Contraindications
- Allergy to class/drug
Adverse Reactions
- QT prolongation
- Myocarditis
- Agranulocytosis in 1%–2% of patients during initial treatment 3 months
- Highest ~3 months into treatment and then decreases
- Other potential side effects:
- Dyslipidemia
- Diabetes
- Decreased seizure threshold
- "Other adverse cardiovascular and respiratory effects" [1]
- "Increased mortality in elderly patients with dementia-related psychosis"[1]
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: