Inhalant abuse: Difference between revisions
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==Background== | ==Background== | ||
* | * First described in the 1950s | ||
* | * Most common abusant in preteens 11-13yo | ||
* | * Most abused: gasoline, solvents like toluene, spray paints, lighter fluid, air fresheners, glue, and electronic cleaners (halogenated hydrocarbons) | ||
* | * Includes: "sniffing", "huffing", "bagging", and "dusting" | ||
==Clinical Features== | ==Clinical Features== | ||
* euphoria, hallucinations | * euphoria, hallucinations | ||
* | * Neuro: impaired motor activity, ataxia, depressed mentation, withdrawal potential | ||
* | * Cardiac: widened QRS, prolonged QT, syncope, arrhythmias | ||
* | * May cause dermal burns | ||
* " | * "Sudden sniffing death" - thought to be occur with sudden catechol surge on a "sensitized" myocardium | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
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==Diagnosis== | ==Diagnosis== | ||
===Workup=== | |||
=== | ===Evaluation=== | ||
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==See Also== | ==See Also== | ||
*[[Toxicology (Main)]] | |||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Tox]] | [[Category:Tox]] | ||
Revision as of 04:16, 30 August 2015
Background
- First described in the 1950s
- Most common abusant in preteens 11-13yo
- Most abused: gasoline, solvents like toluene, spray paints, lighter fluid, air fresheners, glue, and electronic cleaners (halogenated hydrocarbons)
- Includes: "sniffing", "huffing", "bagging", and "dusting"
Clinical Features
- euphoria, hallucinations
- Neuro: impaired motor activity, ataxia, depressed mentation, withdrawal potential
- Cardiac: widened QRS, prolonged QT, syncope, arrhythmias
- May cause dermal burns
- "Sudden sniffing death" - thought to be occur with sudden catechol surge on a "sensitized" myocardium
Differential Diagnosis
Drugs of abuse
- 25C-NBOMe
- Alcohol
- Amphetamines
- Bath salts
- Cocaine
- Ecstasy
- Gamma hydroxybutyrate (GHB)
- Heroin
- Inhalant abuse
- Hydrocarbon toxicity
- Difluoroethane (electronics duster)
- Marijuana
- Kratom
- Phencyclidine (PCP)
- Psilocybin ("magic mushrooms")
- Synthetic cannabinoids
- Chloral hydrate
- Body packing
Diagnosis
Workup
Evaluation
Management
- If teen founded down with sudden death with history of recent inhalant abuse, recommended to try a beta-blocker (propanolol, esmolol) given the myocardial sensitization in addition to CPR, etc