Neuroblastoma (peds): Difference between revisions
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**Chest (15%) | **Chest (15%) | ||
== | ==Clinical Features== | ||
*Depends on location | *Depends on location | ||
**Large, painless abdominal mass | **Large, painless abdominal mass | ||
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*Neutropenia/pancytopenia suggests bone marrow involvement | *Neutropenia/pancytopenia suggests bone marrow involvement | ||
== | ==Differential Diagnosis== | ||
==Diagnosis== | |||
*CXR | *CXR | ||
== | ==Management== | ||
*Admssion for tumor biopsy | *Admssion for tumor biopsy | ||
== | ==See Also== | ||
==References== | |||
[[Category:Peds]] | [[Category:Peds]] | ||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Revision as of 01:50, 10 September 2015
Background
- Arises from primitive ganglion cells of sympathetic nervous system
- Most common neoplasm in 1st yr of life
- May arise anywhere along sympathetic nervous system
- Adrenal gland (40%)
- Abdomen (25%)
- Chest (15%)
Clinical Features
- Depends on location
- Large, painless abdominal mass
- Compression of bowel/bladder
- Horner syndrome
- Spinal cord compression
- Opsoclonus-myoclonus
- Highly a/w neuroblastoma
- Neutropenia/pancytopenia suggests bone marrow involvement
Differential Diagnosis
Diagnosis
- CXR
Management
- Admssion for tumor biopsy