Thiamine: Difference between revisions

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==Adult Dosing==
==Adult Dosing==
*Beriberi
**10-20 mg IM tid x 2wk
***Then 5-30 mg PO qd x1mo
**Intradermal skin test before use if hypersensitivity risk (IM/IV)
*Wet beriberi w/ CHF
**10-30 mg IV tid
****Intradermal skin test before use if hypersensitivity risk (IM/IV)
*Wernicke encephalopathy
**100 mg IV x1
***Then 50-100 mg IM/IV qd
**Intradermal skin test before use if hypersensitivity risk (IM/IV)


==Pediatric Dosing==
==Pediatric Dosing==

Revision as of 18:09, 15 February 2016

Administration

  • Dosage Forms: 50,100,250,500mg
  • Routes of Administration: IM, IV
  • Common Trade Names: Vitamin B1

Adult Dosing

  • Beriberi
    • 10-20 mg IM tid x 2wk
      • Then 5-30 mg PO qd x1mo
    • Intradermal skin test before use if hypersensitivity risk (IM/IV)
  • Wet beriberi w/ CHF
    • 10-30 mg IV tid
        • Intradermal skin test before use if hypersensitivity risk (IM/IV)
  • Wernicke encephalopathy
    • 100 mg IV x1
      • Then 50-100 mg IM/IV qd
    • Intradermal skin test before use if hypersensitivity risk (IM/IV)

Pediatric Dosing

Special Populations

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

Comments

See Also

Thiamine deficiency types

References