Diffuse alveolar hemorrhage: Difference between revisions
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===Differential Diagnosis=== | ===Differential Diagnosis=== | ||
Idiopathic small vessel vasculitis | |||
* Wegener's granulomatosis | |||
* Churg-Straus syndrome | |||
* Microscopic polyangitis | |||
Primary immune complex-mediated vasculitis | |||
* Goodpasture's syndrome | |||
* Henoch-Schonlein purpura | |||
Secondary vasculitis | |||
* Systemic lupus erythematosus | |||
* Rheumatoid arthritis | |||
* Mixed connective tissue disease | |||
* Polymyositis/Dermatomyositis | |||
Acute lung transplant rejection<br /> | |||
Drug induced (ie. chemotherapy, amiodarone, propylthiouracil)<br /> | |||
ARDS<br /> | |||
Coagulopathy<br /> | |||
Pulmonic veno-occlusive disease <br /> | |||
Mitral stenosis | |||
===Diagnosis=== | ===Diagnosis=== | ||
Revision as of 16:17, 13 June 2016
Background
- Diffuse Alveolar Hemorrhage (DAH) is a life-threatening condition.
- It is a subset of Pulmonary hemorrhage involving the microcirculation involving alveolar microvasculature.
- Most commonly the result of systemic vasculitis. [1]
Clinical Features
- Hemoptysis
- Anemia
- Diffuse lung infiltrates
- Acute respiratory failure
Differential Diagnosis
Idiopathic small vessel vasculitis
- Wegener's granulomatosis
- Churg-Straus syndrome
- Microscopic polyangitis
Primary immune complex-mediated vasculitis
- Goodpasture's syndrome
- Henoch-Schonlein purpura
Secondary vasculitis
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Mixed connective tissue disease
- Polymyositis/Dermatomyositis
Acute lung transplant rejection
Drug induced (ie. chemotherapy, amiodarone, propylthiouracil)
ARDS
Coagulopathy
Pulmonic veno-occlusive disease
Mitral stenosis
Diagnosis
Management
Disposition
- ↑ Park M. Diffuse Alveolar Hemorrhage. Tuberc Resp Dis (Seoul) 2013. 74(4):151-162