Naproxen: Difference between revisions
ClaireLewis (talk | contribs) (Created page with "==Administration== *Type: NSAID *Dosage Forms: *Routes of Administration: PO *Common Trade Names: Aleve ==Adult Dosing== *500mg PO BID OR 250mg q6-8h ==Pediatric Dosing==...") |
Neil.m.young (talk | contribs) (Text replacement - "5 mg" to "5mg") |
||
| Line 8: | Line 8: | ||
*500mg PO BID OR 250mg q6-8h | *500mg PO BID OR 250mg q6-8h | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
* | *5mg/kg BID | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
Revision as of 17:31, 20 July 2016
Administration
- Type: NSAID
- Dosage Forms:
- Routes of Administration: PO
- Common Trade Names: Aleve
Adult Dosing
- 500mg PO BID OR 250mg q6-8h
Pediatric Dosing
- 5mg/kg BID
Special Populations
- Pregnancy Rating: C
- Lactation risk: infant risk minimal
Renal Dosing
- Adult: Not recommended if CrCl <30
- Pediatric:
Hepatic Dosing
- Adult: use lowest effective dose
- Pediatric:
Contraindications
- Allergy to class/drug
- peri-CABG
Adverse Reactions
Serious
- GI bleed, gastric ulcer
- Nephrotoxicity
- Angioedema
- Bronchospasm
- CHF, pulmonary edema
- Thrombocytopenia, aplastic anemia, hemolytic anemia, agranulocytosis
- Vasculitis
- SJS/TEN
- Hepatotoxicity (hepatitis, liver failure)
- Aseptic meningitis, seizure
Common
- Nausea, heartburn, constipation
- Edema
- Ecchymosis
- Headache
- Ototoxicity
Pharmacology
- Half-life: 12-17 hours
- Metabolism:
- Excretion: Renal
Mechanism of Action
- NSAID
Comments
See Also
- [NSAIDs]