Sarcoidosis: Difference between revisions

Revision as of 22:05, 1 September 2016

Background

Abnormal collection of inflammatory cells (grandulomas) throughout the body.
- Most common location for granulomas to occur are the lung, skin, heart, and brain.
- Exact cause unknown - thought to be related to an immune reaction to a prior insult such as infection or chemical exposure earlier in life.
- Do not confuse with infectious granulomatous processes such as pulmonary tuberculosis.

Sarcoid Xray - hilar adenopathy

Clinical Features

Fatigue
Weight loss
Arthralgias
Blurry vision
Shortness of breath
Cough
Skin lesions
Asymptomatic (about 5% of cases)

Differential Diagnosis

Malignancy
Tuberculosis
Coccidiodomycosis
Histiocytosis X
Wegener's granulomatosis
Churg-Strauss syndrome
Lupus
Rheumatoid arthritis
Polymyalgia rheumatica

Workup

Management

Disposition

External Links

References

Authors:

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 ==Background==
-Sarcoidosis is the abnormal collection of inflammatory cells called [[grandulomas]] throughout the body. The most common location for these granulomas to occur are the lung, skin, heart, and brain. The exact cause of sarcoidosis is not known, however it is thought to be related to an immune reaction to a prior insult such as infection or chemical exposure earlier in life. This is not to be confused with a infectious granulomatous processes such as [[pulmonary tuberculosis]].
+*Abnormal collection of inflammatory cells (grandulomas) throughout the body.
+**Most common location for granulomas to occur are the lung, skin, heart, and brain.
+**Exact cause unknown - thought to be related to an immune reaction to a prior insult such as infection or chemical exposure earlier in life.
+**Do not confuse with infectious granulomatous processes such as [[pulmonary tuberculosis]].
 [[File:SarcoidXray.png|thumb|Sarcoid Xray - hilar adenopathy]]
 ==Clinical Features==
--fatigue<br />
+*Fatigue
--weight loss<br />
+*Weight loss
--arthralgias<br />
+*Arthralgias
--blurry vision<br />
+*Blurry vision
--shortness of breath<br />
+*Shortness of breath
--cough<br />
+*Cough
--skin lesions<br />
+*Skin lesions
--asymptomatic (about 5% of cases)
+*Asymptomatic (about 5% of cases)
 ==Differential Diagnosis==
--Cancer<br />
+*Malignancy
--Tuberculosis<br />
+*Tuberculosis
--Coccidiodomycosis<br />
+*Coccidiodomycosis
--Histiocytosis X<br />
+*Histiocytosis X
--Wegener's granulomatosis<br />
+*Wegener's granulomatosis
--Churg-Strauss syndrome<br />
+*Churg-Strauss syndrome
--Lupus<br />
+*Lupus
--Rheumatoid arthritis<br />
+*Rheumatoid arthritis
--Polymyalgia rheumatica
+*Polymyalgia rheumatica
 ==Workup==
 ==Management==
 ==Disposition==
 ==See Also==
 ==External Links==
 ==References==