Template:Male urethritis treatment

Uncomplicated Infection

Treatment to cover both gonorrhea and chlamydia Typically, treatment for both gonorrhea and chlamydia is indicated, if one entity is suspected.

Standard

• Gonorrhea
  • Ceftriaxone IM x 1
    • 500 mg, if weight <150 kg
    • 1 g, if weight ≥150 kg
• Chlamydia
  • Doxycycline 100 mg PO BID x 7 days

Ceftriaxone contraindicated

• Gonorrhea
  • Gentamicin 240 mg IM x 1 PLUS azithromycin 2 g PO x 1, OR
  • Cefixime 800 mg PO x 1
• Chlamydia^
  • Doxycycline 100 mg PO BID x 7 days

^Additional chlamydia coverage only needed if treated with cefixime only

Partner treatment

• Gonorrhea
  • Cefixime 800mg PO x 1
  • Nonpregnant: doxycycline 100mg PO BID x 7 days, OR
  • Pregnant: azithromycin 1g PO x 1

Recurrent or Persistent

Target M. genitalium

• Moxifloxacin 400 mg daily x 7 days

Consider coverage of trichomonas, among men who have sex with women

• Metronidazole 2 gm PO x 1, OR
• Tinidazole 2 gm PO x 1