Anticonvulsants

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Pediatric Anticonvulsants Table

Drug Dose Infusion Rate Age Comments/Cautions
Levetiracetam 60 mg/kg/dose IV/IO (MAX 3000 mg/dose) Over 5 minutes Any Most commonly used agent
Fosphenytoin 20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM (MAX 1000 PE/dose) Over 10 minutes Any Choose alternate drug if on phytoin at home; may decrease BP/HR
Valproic acid 40 mg/kg/dose IV/IO (MAX 3000 mg/dose) Over 10 minutes >2 years Caution in patients with liver dysfunciton, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay
Phenytoin 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) Over 20 minutes Any Choose alternate drug if on phytoin at home; may decrease BP/HR
Phenobarbital 20 mg/kg/dose IV/IO (MAX 1000 mg/dose) Over 20 minutes <6 months Repiratory depression, espeically in combination with benzos

See Also